Department of Physiology

  • Korea, Republic of

Research Output

  • 1971 Citations
  • 23 h-Index
  • 76 Article
  • 4 Patent
  • 2 Review article
  • 1 Letter
2020

Genome editing methods in animal models

Lee, H., Yoon, D. E. & Kim, K., 2020 Jan 2, In : Animal Cells and Systems. 24, 1, p. 8-16 9 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Mud Therapy Combined with Core Exercise for Chronic Nonspecific Low Back Pain: A Pilot, Single-Blind, Randomized Controlled Trial

Hahm, S. C., Shin, H. J., Lee, M. G., Lee, S. J. & Cho, H. Y., 2020, In : Evidence-based Complementary and Alternative Medicine. 2020, 7547452.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling

Yang, K. E., Jang, H. J., Hwang, I. H., Hong, E. M., Lee, M. G., Lee, S., Jang, I. S. & Choi, J. S., 2020 Mar, In : Journal of Ginseng Research. 44, 2, p. 341-349 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2019

CCN5 Reduces Ligamentum Flavum Hypertrophy by Modulating the TGF-β Pathway

Ye, S., Kwon, W. K., Bae, T., Kim, S., Lee, J. B., Cho, T. H., Park, J. Y., Kim, K., Hur, J. K. & Hur, J. W., 2019 Dec 1, In : Journal of Orthopaedic Research. 37, 12, p. 2634-2644 11 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Effects of therapeutic exercise on sea sand on pain, fatigue, and balance in patients with chronic ankle instability: a feasibility study

Shin, H. J., Kim, S. H., Jeon, E. T., Lee, M-G., Lee, S. J. & Cho, H. Y., 2019 Jul 1, In : The Journal of sports medicine and physical fitness. 59, 7, p. 1200-1205 6 p.

Research output: Contribution to journalArticle

Evolution of CRISPR towards accurate and efficient mammal genome engineering

Ryu, S. M., Hur, J. W. & Kim, K., 2019, In : BMB reports. 52, 8, p. 475-481 7 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Lif, a novel myokine, protects against amyloid-beta-induced neurotoxicity via akt-mediated autophagy signaling in hippocampal cells

Lee, H. J., Lee, J. O., Lee, Y. W., Kim, S. A., Seo, I. H., Han, J. A., Kang, M. J., Kim, S. J., Cho, Y. H., Park, J. J., Choi, J. I., Park, S. H. & Kim, H. S., 2019, In : International Journal of Neuropsychopharmacology. 22, 6, p. 402-414 13 p., pyz016.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Short-term benefits of balneotherapy for patients with chronic pelvic pain: a pilot study in Korea

Min, K. J., Choi, H., Tae, B. S., Lee, M. G., Lee, S. J. & Hong, K. D., 2019 Jan 1, (Accepted/In press) In : Journal of Obstetrics and Gynaecology.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The Effect of Natural Ocean Sound Exposure and Ocean-Side Relaxation on Chronic Tinnitus Patients: A Pilot Study in Korea

Lim, K. H., Nam, K. J., Rah, Y. C., Cha, J., Lee, S. J., Lee, M. G. & Choi, J., 2019 Jan 1, (Accepted/In press) In : Ear, Nose and Throat Journal.

Research output: Contribution to journalArticle

Open Access
2018

Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy

Ryu, S. M., Koo, T., Kim, K., Lim, K., Baek, G., Kim, S. T., Kim, H. S., Kim, D. E., Lee, H., Chung, E. & Kim, J. S., 2018 Jul 1, In : Nature Biotechnology. 36, 6, p. 536-539 4 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Adipogenic and lipolytic effects of ascorbic acid in ovariectomized rats

Kim, B., Choi, K. M., Yim, H. S., Park, H. T., Yim, J. H. & Lee, M. G., 2018 Jan, In : Yonsei medical journal. 59, 1, p. 85-91 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway

Cui, Z. Y., Park, S. J., Jo, E., Hwang, I. H., Lee, K. B., Kim, S. W., Kim, D. J., Joo, J. C., Hong, S. H., Lee, M. G. & Jang, I. S., 2018 Dec 1, In : Cell Death Discovery. 4, 1, 62.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Cordyceps militaris extract inhibits the NF-κB pathway and induces apoptosis through MKK7-JNK signaling activation in TK-10 human renal cell carcinoma

Park, S. J., Jang, H. J., Hwang, I. H., Kim, J. M., Jo, E., Lee, M. G., Jang, I. S. & Joo, J. C., 2018, In : Natural Product Communications. 13, 4, p. 465-470 6 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Response to "unexpected mutations after CRISPR-Cas9 editing in vivo"

Kim, S. T., Park, J., Kim, D., Kim, K., Bae, S., Schlesner, M. & Kim, J. S., 2018 Apr 3, In : Nature Methods. 15, 4, p. 239-240 2 p.

Research output: Contribution to journalLetter

15 Citations (Scopus)

Toll-like receptor expression in pulmonary sensory neurons in the bleomycin-induced fibrosis model

Jung, W. J., Lee, S. Y., Choi, S. I., Kim, B. K., Lee, E. J., In, K. H. & Lee, M. G., 2018 Mar, In : PloS one. 13, 3, e0193117.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Whole-body vibration improves ankle spasticity, balance, and walking ability in individuals with incomplete cervical spinal cord injury

In, T., Jung, K., Lee, M-G. & Cho, H. Y., 2018 Jan 1, In : NeuroRehabilitation. 42, 4, p. 491-497 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR

Lee, S. H., Yu, J., Hwang, G. H., Kim, S., Kim, H. S., Ye, S., Kim, K., Park, J., Park, D. Y., Cho, Y. K., Kim, J. S. & Bae, S., 2017 Aug 28, In : Oncogene. 36, 49, p. 6823-6829 7 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Genes for judgment of light pollution and device judging light pollution using the same

Park, J. J. & Lee, E. I., 2017 Oct 25, Patent No. 10-1792222

Research output: Patent

Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration

Kim, K., Park, S. W., Kim, J. H., Lee, S. H., Kim, D., Koo, T., Kim, K. E., Kim, J. H. & Kim, J. S., 2017 Mar, In : Genome Research. 27, 3, p. 419-426 8 p.

Research output: Contribution to journalArticle

Open Access
65 Citations (Scopus)

Genome-wide target specificities of CRISPR RNA-guided programmable deaminases

Kim, D., Lim, K., Kim, S. T., Yoon, S. H., Kim, K., Ryu, S. M. & Kim, J. S., 2017 May 1, In : Nature Biotechnology. 35, 5, p. 475-480 6 p.

Research output: Contribution to journalArticle

110 Citations (Scopus)

Houttuynia cordata Thunb Promotes Activation of HIF-1A-FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells

Kim, J. M., Hwang, I. H., Jang, I. S., Kim, M., Bang, I. S., Park, S. J., Chung, Y. J., Joo, J. C. & Lee, M. G., 2017 Sep 1, In : Integrative Cancer Therapies. 16, 3, p. 360-372 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

Kim, E., Koo, T., Park, S. W., Kim, D., Kim, K., Cho, H. Y., Song, D. W., Lee, K. J., Jung, M. H., Kim, S., Kim, J. H., Kim, J. H. & Kim, J. S., 2017 Feb 21, In : Nature communications. 8, 14500.

Research output: Contribution to journalArticle

Open Access
191 Citations (Scopus)

Modified Panax ginseng extract regulates autophagy by AMPK signaling in A549 human lung cancer cells

Yoo, H. S., Kim, J. M., Jo, E., Cho, C. K., Lee, S. Y., Kang, H. S., Lee, M-G., Yang, P. Y. & Jang, I. S., 2017 Jun 1, In : Oncology Reports. 37, 6, p. 3287-3296 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Myofibroblast in the ligamentum flavum hypertrophic activity

Hur, J. W., Bae, T., Ye, S., Kim, J. H., Lee, S., Kim, K., Lee, S. H., Kim, J. S., Lee, J. B., Cho, T. H., Park, J. Y. & Hur, J. K., 2017 Aug 1, In : European Spine Journal. 26, 8, p. 2021-2030 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Neoagarohexaose-mediated activation of dendritic cells via Toll-like receptor 4 leads to stimulation of natural killer cells and enhancement of antitumor immunity

Lee, M. H., Jang, J. H., Yoon, G. Y., Lee, S. J., Lee, M. G., Kang, T. H., Han, H. D., Kim, H. S., Choi, W. S., Park, W. S., Park, Y. M. & Jung, I. D., 2017, In : BMB reports. 50, 5, p. 263-268 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Short-term exposure to dim light at night disrupts rhythmic behaviors and causes neurodegeneration in fly models of tauopathy and Alzheimer's disease

Kim, M., Subramanian, M., Cho, Y. H., Kim, G. H., Lee, E. I. & Park, J. J., 2017 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2016

Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon

Lee, S. Y., Kim, H., Kim, K., Lee, H., Lee, S. & Lee, D., 2016 May 27, In : Scientific reports. 6, 26923.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Tetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells

Hwang, I. H., Park, J., Kim, J. M., Il Kim, S., Choi, J. S., Lee, K. B., Yun, S. H., Lee, M. G., Park, S. J. & Jang, I. S., 2016 Sep, In : FASEB Journal. 30, 9, p. 3107-3116 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

The effect of an IκB-kinase-β(IKKβ) inhibitor on tobacco smoke-induced pulmonary inflammation

Choi, S. I., Lee, S. Y., Jung, W. J., Lee, S. H., Lee, E. J., Min, K. H., Hur, G. Y., Lee, S. H., Lee, S. Y., Kim, J. H., Shin, C., Shim, J. J., In, K. H., Kang, K. H. & Lee, M. G., 2016 Apr 20, In : Experimental Lung Research. 42, 4, p. 182-189 8 p.

Research output: Contribution to journalArticle

2015

Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis

Lee, H., Jeong, H., Park, S., Yoo, W., Choi, S., Choi, K., Lee, M. G., Lee, M., Cha, D., Kim, Y. S., Han, J., Kim, W., Park, S. H. & Oh, J., 2015 Jun 1, In : EMBO Molecular Medicine. 7, 6, p. 819-830 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Heat shock protein X purified from Mycobacterium tuberculosis enhances the efficacy of dendritic cells-based immunotherapy for the treatment of allergic asthma

Kim, H. Y., Kang, H. K., Cho, J., Jung, I. D., Yoon, G. Y., Lee, M. G., Shin, S. J., Park, W. S., Park, J. H., Ryu, S. W., Park, Y. M. & You, J. C., 2015, In : BMB reports. 48, 3, p. 178-183 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species

Yu, S., Jang, Y., Paik, D., Lee, E. I. & Park, J. J., 2015 Aug 21, In : Biochemical and Biophysical Research Communications. 465, 4, p. 845-850 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Overexpression of malic enzyme in the larval stage extends Drosophila lifespan

Kim, G. H., Lee, Y. E., Lee, G. H., Cho, Y. H., Lee, Y. N., Jang, Y., Paik, D. & Park, J. J., 2015 Jan 9, In : Biochemical and Biophysical Research Communications. 456, 2, p. 676-682 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

P31comet-induced cell death is mediated by binding and inactivation of Mad2

Shin, H. J., Park, E. R., Yun, S. H., Kim, S. H., Jung, W. H., Woo, S. R., Joo, H. Y., Jang, S. H., Chung, H. Y., Hong, S. H., Cho, M. H., Park, J. J., Yun, M. & Lee, K. H., 2015 Nov 6, In : PloS one. 10, 11, e0141523.

Research output: Contribution to journalArticle

2 Citations (Scopus)

SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia

Joo, H. Y., Yun, M., Jeong, J., Park, E. R., Shin, H. J., Woo, S. R., Jung, J. K., Kim, Y. M., Park, J. J., Kim, J. & Lee, K. H., 2015 Jun 12, In : Biochemical and Biophysical Research Communications. 462, 4, p. 294-300 7 p., 33865.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2014

A potential protein adjuvant derived from Mycobacterium tuberculosis Rv0652 enhances dendritic cells-based tumor immunotherapy

Lee, S. J., Shin, S. J., Lee, M. H., Lee, M-G., Kang, T. H., Park, W. S., Soh, B. Y., Park, J. H., Shin, Y. K., Kim, H. W., Yun, C. H., Jung, I. D. & Park, Y. M., 2014 Aug 7, In : PLoS One. 9, 8, e104351.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by mycobacterium tuberculosis heat shock protein X

Jung, I. D., Shin, S. J., Lee, M. G., Kang, T. H., Han, H. D., Lee, S. J., Kim, W. S., Kim, H. M., Park, W. S., Kim, H. W., Yun, C. H., Lee, E. K., Wu, T. C. & Park, Y. M., 2014 Aug 1, In : Journal of Immunology. 193, 3, p. 1233-1245 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells

Lee, H., Lee, H., Chin, H., Kim, K. & Lee, D., 2014, In : Oncotarget. 5, 13, p. 5138-5152 15 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)
2013

Ascorbic acid enhances adipogenesis of 3T3-L1 murine preadipocyte through differential expression of collagens

Kim, B., Choi, K. M., Yim, H. S. & Lee, M. G., 2013 Dec 11, In : Lipids in Health and Disease. 12, 1, 182.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Effect of 1-methyl-D-tryptophan and adoptive transfer of dendritic cells on polymicrobial sepsis induced by cecal content injection

Yim, H. S., Choi, K. M., Kim, B., Jung, I. D., Park, Y. M., Kang, Y. K. & Lee, M. G., 2013 Sep, In : Microbiology and Immunology. 57, 9, p. 633-639 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

Full genome analysis of a novel adenovirus from the South Polar skua (Catharacta maccormicki) in Antarctica

Park, Y. M., Kim, J. H., Gu, S. H., Lee, S. Y., Lee, M. G., Kang, Y. K., Kang, S. H., Kim, H. J. & Song, J. W., 2012 Jan 5, In : Virology. 422, 1, p. 144-150 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Low-dose radiation induces drosophila innate immunity through toll pathway activation

Seong, K. M., Kim, C. S., Lee, B. S., Nam, S. Y., Yang, K. H., Kim, J. Y., Park, J. J., Min, K. J. & Jin, Y. W., 2012 Mar, In : Journal of Radiation Research. 53, 2, p. 242-249 8 p.

Research output: Contribution to journalReview article

Open Access
20 Citations (Scopus)

Misexpression screen delineates novel genes controlling Drosophila lifespan

Paik, D., Jang, Y. G., Lee, Y. E., Lee, Y. N., Yamamoto, R., Gee, H. Y., Yoo, S., Bae, E., Min, K. J., Tatar, M. & Park, J. J., 2012 May, In : Mechanisms of Ageing and Development. 133, 5, p. 234-245 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Over-expression of human clusterin increases stress resistance and extends lifespan in Drosophila melanogaster

Lee, Y. N., Shim, Y. J., Kang, B. H., Park, J. J. & Min, B. H., 2012 Apr 20, In : Biochemical and biophysical research communications. 420, 4, p. 851-856 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2011

Chronic hyperosmotic stress converts gabaergic inhibition into excitation in vasopressin and oxytocin neurons in the rat

Kim, J. S., Kim, W. B., Kim, Y. B., Lee, Y., Kim, Y. S., Shen, F. Y., Lee, S. W., Park, D., Choi, H. J., Hur, J., Park, J. J., Han, H. C., Colwell, C. S., Cho, Y. W. & Kim, Y. I., 2011 Sep 14, In : Journal of Neuroscience. 31, 37, p. 13312-13322 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Direct activation of guinea pig vagal afferent neurons by FMRFamide

Lee, M. G., Park, J. Y., Park, Y. K. & Undem, B. J., 2011 Aug 24, In : Neuroreport. 22, 12, p. 609-612 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Dopamine signalling in mushroom bodies regulates temperature-preference behaviour in Drosophila

Bang, S., Hyun, S., Hong, S. T., Kang, J., Jeong, K., Park, J. J., Choe, J. & Chung, J., 2011 Mar, In : PLoS Genetics. 7, 3, e1001346.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Mycobacterium tuberculosis lpdC, Rv0462, induces dendritic cell maturation and Th1 polarization

Heo, D. R., Shin, S. J., Kim, W. S., Noh, K. T., Park, J. W., Son, K. H., Park, W. S., Lee, M. G., Kim, D., Shin, Y. K., Jung, I. D. & Park, Y. M., 2011 Aug 5, In : Biochemical and biophysical research communications. 411, 3, p. 642-647 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)