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Research Output 1987 2020

  • 3418 Citations
  • 32 h-Index
  • 198 Article
  • 1 Chapter
2020
Stem cells
Mesenchymal Stromal Cells
Colorectal Neoplasms
Cells
Neoplasms
2019

Application of the Quality-by-Design (QbD) Approach for Erythropoietin Alpha Purification

Kim, T. K., Seo, K. S., Kwon, S. O., Little, T. A., Kim, M. & Kim, C. W., 2019 Jan 1, In : Bulletin of the Korean Chemical Society.

Research output: Contribution to journalArticle

Erythropoietin
Purification
Flow rate
Endotoxins
Regression analysis

Applying the Quality by Design to Robust Optimization and Design Space Define for Erythropoietin Cell Culture Process

Kim, T. K., Seo, K. S., Kwon, S. O., Kim, H. S., Kim, J. H., Jeong, M. W., Little, T. A., Kim, M. & Kim, C. W., 2019 Jan 1, (Accepted/In press) In : Bulletin of the Korean Chemical Society.

Research output: Contribution to journalArticle

Erythropoietin
Cell culture
Dissolved oxygen
Bioreactors
Regression analysis

Correlation between the results of two analytical methods for measuring measles virus neutralizing antibodies in source plasma and therapeutic immunoglobulin products

Hong, J., Kim, D., Won, Y., Yoon, J., Park, K. J., Oh, J. & Kim, C. W., 2019 Jan 1, In : Biologicals.

Research output: Contribution to journalArticle

Open Access
Measles virus
Plasma sources
Neutralizing Antibodies
Viruses
Antibodies

Development of a new 15-valent pneumococcal conjugate vaccine (PCV15) and evaluation of its immunogenicity

Lee, C., Choi, S. K., Kim, R. K., Kim, H., Whang, Y. H., Pharm, H., Cheon, H., Yoon, D. Y., Kim, C. W., Baik, Y. O., Park, S. S. & Lee, I., 2019 Jan 1, In : Biologicals.

Research output: Contribution to journalArticle

Conjugate Vaccines
Pneumococcal Vaccines
Vaccines
Antibodies
Antigens
1 Citation (Scopus)

Exogenous CLASP2 protein treatment enhances wound healing in vitro and in vivo

Kim, M. J., Lee, Y. S., Yoo, Y. M., Choi, J. J., Kim, H. N., Kang, C., Yu, J. M., Moon, S. H., Kim, A. & Kim, C. W., 2019 Jan 1, In : Wound Repair and Regeneration.

Research output: Contribution to journalArticle

Wound Healing
Proteins
Fibroblasts
Microtubules
Skin

Improved production of clavulanic acid by reverse engineering and overexpression of the regulatory genes in an industrial Streptomyces clavuligerus strain

Cho, H. S., Jo, J. C., Shin, C. H., Lee, N., Choi, J. S., Cho, B. K., Roe, J. H., Kim, C. W., Kwon, H. J. & Yoon, Y. J., 2019 Jan 1, In : Journal of Industrial Microbiology and Biotechnology.

Research output: Contribution to journalArticle

Clavulanic Acid
Reverse engineering
Streptomyces
Regulator Genes
Genes

Quality by Design characterization of the perfusion culture process for recombinant FVIII

Kim, Y. J., Paik, S. H., Han, S. K., Lee, S., Jeong, Y., Kim, J. Y. & Kim, C. W., 2019 May 1, In : Biologicals. 59, p. 37-46 10 p.

Research output: Contribution to journalArticle

Open Access
Factor VIII
Cell Culture Techniques
Perfusion
Bioreactors
Tyrosine

Transgelin Depletion is Critical for the TGFβ1-mediated Initiation of PLCγ1-Cofilin-driven Morphological and Migratory Changes in MDA-MB-231 Cells

Raymundo, B. R., Oh, I. R., Kim, M. J. & Kim, C. W., 2019 Dec 1, In : Bulletin of the Korean Chemical Society. 40, 12, p. 1191-1201 11 p.

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Transforming Growth Factors
Plasticity
transgelin
phospholipase C1
2018
3 Citations (Scopus)

A randomized, observer-blinded, equivalence trial comparing two variations of Euvichol®, a bivalent killed whole-cell oral cholera vaccine, in healthy adults and children in the Philippines

Russo, P., Ligsay, A. D., Olveda, R., Choi, S. K., Kim, D. R., Park, J. Y., Park, J. Y., Syed, K. A., Dey, A., Kim, Y. H., Lee, S. H., Kim, J., Chon, Y., Digilio, L., Kim, C. W. & Excler, J. L., 2018 Jul 5, In : Vaccine. 36, 29, p. 4317-4324 8 p.

Research output: Contribution to journalArticle

Cholera Vaccines
cholera
Philippines
mouth
seroconversion
1 Citation (Scopus)

Characterisation of the site-specific monoPEGylated rhG-CSF analogue pegteograstim

Hong, J., Lee, B., Kang, K., Lee, S. H., Ryu, J., Jung, G., Oh, J., Jo, E. C. & Kim, C. W., 2018 Jan 1, In : Biologicals. 51, p. 54-61 8 p.

Research output: Contribution to journalArticle

Pharmacodynamics
Pharmacokinetics
Chemotherapy
Chromatography
Escherichia coli

Coagulant Effect and Tolerability of Yeast-Produced Recombinant Batroxobin in Healthy Adult Subjects

Choi, S. K., Kim, C. W., Kim, J. T., Seomun, Y., Park, M. S. & Kim, C. O., 2018 Sep 1, In : Clinical Drug Investigation. 38, 9, p. 829-835 7 p.

Research output: Contribution to journalArticle

Batroxobin
Coagulants
Healthy Volunteers
Yeasts
Thrombin Time
1 Citation (Scopus)
Macrophages
Coculture Techniques
Stem cells
Mesenchymal Stromal Cells
Dry Eye Syndromes

Development of a Novel Nonradioisotopic Assay and Cdc25B Overexpression Cell Lines for Use in Screening for Cdc25B Inhibitors

Ha, G. S., Lee, C. M. & Kim, C. W., 2018 Oct 1, In : Yonsei Medical Journal. 59, 8, p. 995-1003 9 p.

Research output: Contribution to journalArticle

CDC2 Protein Kinase
Cell Line
HeLa Cells
Phosphotransferases
cdc25 Phosphatases
2 Citations (Scopus)

Enhanced expression of soluble antibody fragments by low-temperature and overdosing with a nitrogen source

Kim, S. J., Ha, G. S., Lee, G., Lim, S. I., Lee, C. M., Yang, Y. H., Lee, J. M., Kim, J. E., Lee, J. H., Shin, Y. U., Kim, C. W. & Lee, D. E., 2018 Aug 1, In : Enzyme and Microbial Technology. 115, p. 9-15 7 p.

Research output: Contribution to journalArticle

Immunoglobulin Fragments
Nitrogen
Fermentation
Temperature
Escherichia coli

Neuregulin-1 accelerates corneal epithelial wound healing

Jeong, W. Y., Yoo, H. Y. & Kim, C. W., 2018 Feb 15, (Accepted/In press) In : Growth Factors. p. 1-9 9 p.

Research output: Contribution to journalArticle

Neuregulin-1
Wound Healing
Stem cells
Epithelial Cells
Stem Cells

Validation of Monosaccharide Composition Assay Using HPLC-UV Platform for Monoclonal Antibody Products in Compliance with ICH Guideline

Kwon, O., Oh, I. U., Oh, M. J., Hong, S. H., Kim, C. W. & An, H. J., 2018 Dec 1, In : Bulletin of the Korean Chemical Society. 39, 12, p. 1394-1399 6 p.

Research output: Contribution to journalArticle

Monosaccharides
Quality control
Assays
Monoclonal Antibodies
Chemical analysis
1 Citation (Scopus)

β-cellulin promotes the proliferation of corneal epithelial stem cells through the phosphorylation of erk1/2

Jeong, W. Y., Yoo, H. Y. & Kim, C. W., 2018 Jan 1, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Phosphorylation
Stem cells
Wound Healing
Stem Cells
Epithelial Cells
2017

Characterisation of the site-specific monoPEGylated rhG-CSF analogue pegteograstim

Hong, J., Lee, B., Kang, K., Lee, S. H., Ryu, J., Jung, G., Oh, J., Jo, E. C. & Kim, C. W., 2017, (Accepted/In press) In : Biologicals.

Research output: Contribution to journalArticle

Pharmacodynamics
Pharmacokinetics
Chemotherapy
Chromatography
Escherichia coli
9 Citations (Scopus)

CXCR4 overexpression in human adipose tissue-derived stem cells improves homing and engraftment in an animal limb ischemia model

Kim, M., Kim, D. I., Kim, E. K. & Kim, C. W., 2017, In : Cell Transplantation. 26, 2, p. 191-204 14 p.

Research output: Contribution to journalArticle

Stem cells
Adipose Tissue
Animals
Stem Cells
Ischemia
8 Citations (Scopus)

Downregulation of transgelin blocks interleukin-8 utilization and suppresses vasculogenic mimicry in breast cancer cells

Aikins, A. R., Kim, M. J., Raymundo, B. & Kim, C. W., 2017 Mar 1, In : Experimental Biology and Medicine. 242, 6, p. 573-583 11 p.

Research output: Contribution to journalArticle

Interleukin-8
Down-Regulation
Cells
Breast Neoplasms
Neoplasms
3 Citations (Scopus)

Extremely low-frequency electromagnetic field induces neural differentiation of hBM-MSCs through regulation of (Zn)-metallothionein-3

Aikins, A. R., Hong, S. W., Kim, H. J., Yoon, C. H., Chung, J. H., Kim, M. & Kim, C. W., 2017, (Accepted/In press) In : Bioelectromagnetics.

Research output: Contribution to journalArticle

Electromagnetic Fields
Bone Marrow
Zinc
Neurodegenerative Diseases
Alzheimer Disease
4 Citations (Scopus)
Electromagnetic Fields
Stem cells
Mesenchymal Stromal Cells
Electromagnetic fields
Bone

Structural and biochemical characterization of FabK from Thermotoga maritima

Ha, B. H., Shin, S. C., Moon, J. H., Keum, G., Kim, C. W. & Kim, E. E. K., 2017 Jan 22, In : Biochemical and Biophysical Research Communications. 482, 4, p. 968-974 7 p.

Research output: Contribution to journalArticle

Thermotoga maritima
Flavin Mononucleotide
Crystal structure
Acyl Carrier Protein
Biosynthesis
9 Citations (Scopus)

Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors

Lee, J. H., Shin, S. C., Seo, S. H., Seo, Y. H., Jeong, N., Kim, C. W., Kim, E. E. K. & Keum, G., 2017 Jan 15, In : Bioorganic and Medicinal Chemistry Letters. 27, 2, p. 237-241 5 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Cells
Cell Line
X ray crystallography
X Ray Crystallography
3 Citations (Scopus)

Unique binding mode of Evogliptin with human dipeptidyl peptidase IV

Lee, H. K., Kim, M. K., Kim, H. D., Kim, H. J., Kim, J. W., Lee, J. O., Kim, C. W. & Kim, E. E. K., 2017 Dec 16, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 452-459 8 p.

Research output: Contribution to journalArticle

Dipeptidyl Peptidase 4
Dipeptidyl-Peptidase IV Inhibitors
Republic of Korea
Medical problems
Hydrophobic and Hydrophilic Interactions
2016
7 Citations (Scopus)

Considerations of critical quality attributes in the analytical comparability assessment of biosimilar products

Kwon, O., Joung, J., Park, Y., Kim, C. W. & Hong, S. H., 2016 Dec 28, (Accepted/In press) In : Biologicals.

Research output: Contribution to journalArticle

Biosimilar Pharmaceuticals
Product development
Marketing
Molecular weight
Chemical analysis
6 Citations (Scopus)
Human Growth Hormone
Hyaluronic Acid
Growth Hormone
Hot Temperature
High Pressure Liquid Chromatography
6 Citations (Scopus)

Dual-blocking of PI3K and mTOR improves chemotherapeutic effects on SW620 human colorectal cancer stem cells by inducing differentiation

Kim, M. J., Koo, J. E., Han, G. Y., Kim, B., Lee, Y. S., Ahn, C. & Kim, C. W., 2016, In : Journal of Korean Medical Science. 31, 3, p. 360-370 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Neoplastic Stem Cells
Sirolimus
Cell Differentiation
Colorectal Neoplasms
2 Citations (Scopus)

Evaluation of safety and efficacy of adipose-derived stem cells in rat myocardial infarction model using hexadecyl-4-[124I]iodobenzoate for cell tracking

Kim, M. H., Lee, K. C., An, G. I., Woo, S. K., Park, N. W., Kim, B. I., Eom, K. D., Kim, K. I., Lee, T. S., Kim, C. W., Yoo, J., Kang, J. H. & Lee, Y. J., 2016 Feb 1, In : Applied Radiation and Isotopes. 108, p. 116-123 8 p.

Research output: Contribution to journalArticle

myocardial infarction
stem cells
rats
safety
evaluation
7 Citations (Scopus)

GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes

Kim, S. H., Kim, H. J. & Kim, C. W., 2016 May 13, In : Experimental & molecular medicine. 48, p. e233

Research output: Contribution to journalArticle

Podocytes
1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Glucocorticoids
Phosphotransferases
3 Citations (Scopus)

Human amniotic membrane extracts have anti-inflammatory effects on damaged human corneal epithelial cells in vitro

Lee, H. N., Bernardo, R., Han, G. Y., Kim, G. Y., Kim, J. S., Jung, W. Y., Kim, K. N., Kim, J. C. & Kim, C. W., 2016, In : Journal of Hard Tissue Biology. 25, 3, p. 282-287 6 p.

Research output: Contribution to journalArticle

Amnion
Anti-Inflammatory Agents
Epithelial Cells
Membranes
Inflammation

Inhibition of c-Yes induces differentiation of HT-29 human colon cancer stem cells through midbody elongation

Jung, J., Choi, S. C., Lee, H. N., Han, G. Y. & Kim, C. W., 2016 Jun 1, In : Tissue Engineering and Regenerative Medicine. 13, 3, p. 261-269 9 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Stem cells
Colonic Neoplasms
Elongation
Assays
11 Citations (Scopus)

Targeting ROR1 inhibits the self-renewal and invasive ability of glioblastoma stem cells

Jung, E. H., Lee, H. N., Han, G. Y., Kim, M. J. & Kim, C. W., 2016, (Accepted/In press) In : Cell Biochemistry and Function.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Glioblastoma
Stem cells
Stem Cells
Receptor Tyrosine Kinase-like Orphan Receptors
2015
24 Citations (Scopus)

A randomized, non-inferiority trial comparing two bivalent killed, whole cell, oral cholera vaccines (Euvichol vs Shanchol) in the Philippines

Baik, Y. O., Choi, S. K., Olveda, R. M., Espos, R. A., Ligsay, A. D., Montellano, M. B., Yeam, J. S., Yang, J. S., Park, J. Y., Kim, D. R., Desai, S. N., Singh, A. P., Kim, I. Y., Kim, C. W. & Park, S. N., 2015 Nov 17, In : Vaccine. 33, 46, p. 6360-6365 6 p.

Research output: Contribution to journalArticle

Cholera Vaccines
cholera
Philippines
mouth
vaccines
1 Citation (Scopus)
Human Growth Hormone
Hyaluronic Acid
Growth Hormone
Hot Temperature
sulfoxide
5 Citations (Scopus)

Enhancing proliferation and ECM expression of human ACL fibroblasts by sonic vibration

Jiang, Y. Y., Park, J. K., Yoon, H. H., Choi, H., Kim, C. W. & Seo, Y. K., 2015 Jan 1, In : Preparative Biochemistry and Biotechnology. 45, 5, p. 476-490 15 p.

Research output: Contribution to journalArticle

Anterior Cruciate Ligament
Ligaments
Fibroblasts
Vibration
Extracellular Matrix
3 Citations (Scopus)

Evaluation of a 64Cu-labeled 1,4,7-triazacyclononane, 1-glutaric acid-4,7 acetic acid (NODAGA)-galactose-bombesin analogue as a PET imaging probe in a gastrin-releasing peptide receptor-expressing prostate cancer xenograft model

Kim, M. H., Park, J. A., Woo, S. K., Lee, K. C., An, G. I., Kim, B. S., Kim, K. I., Lee, T. S., Kim, C. W., Kim, K. M., Kang, J. H. & Lee, Y. J., 2015 Mar 1, In : International Journal of Oncology. 46, 3, p. 1159-1168 10 p.

Research output: Contribution to journalArticle

Bombesin Receptors
Bombesin
Galactose
Heterografts
Positron-Emission Tomography
5 Citations (Scopus)
Apoferritins
Electromagnetic Fields
Ferritins
Stem cells
Mesenchymal Stromal Cells
5 Citations (Scopus)

Human amniotic membrane-derived stromal cells (hAMSC) interact depending on breast cancer cell type through secreted molecules

Kim, S. H., Bang, S. H., Kang, S. Y., Park, K. D., Eom, J. H., Oh, I. U., Yoo, S. H., Kim, C. W. & Baek, S. Y., 2015 Feb 1, In : Tissue and Cell. 47, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

Amnion
Stromal Cells
Breast Neoplasms
MCF-7 Cells
Cell- and Tissue-Based Therapy
7 Citations (Scopus)

Illite improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease through Akt/CREB and GSK-3β phosphorylation in the brain

Jeon, S., Park, J. E., Lee, J., Liu, Q. F., Jeong, H. J., Pak, S. C., Yi, S., Kim, M. H., Kim, C. W., Park, J. K., Kim, G. W. & Koo, B. S., 2015 Feb 3, In : Journal of Ethnopharmacology. 160, p. 69-77 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Alzheimer Disease
Phosphorylation
Brain
illite
10 Citations (Scopus)

Longitudinal monitoring adipose-derived stem cell survival by PET imaging hexadecyl-4-124I-iodobenzoate in rat myocardial infarction model

Kim, M. H., Woo, S. K., Lee, K. C., An, G. I., Pandya, D., Park, N. W., Nahm, S. S., Eom, K. D., Kim, K. I., Lee, T. S., Kim, C. W., Kang, J. H., Yoo, J. & Lee, Y. J., 2015 Jan 2, In : Biochemical and Biophysical Research Communications. 456, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

Iodobenzoates
Positron emission tomography
Stem cells
Positron-Emission Tomography
Rats
14 Citations (Scopus)

Modulation of biomechanical properties of hyaluronic acid hydrogels by crosslinking agents

Choi, S. C., Yoo, M. A., Lee, S. Y., Lee, H. J., Son, D. H., Jung, J., Noh, I. & Kim, C. W., 2015 Sep 1, In : Journal of Biomedical Materials Research - Part A. 103, 9, p. 3072-3080 9 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Hydrogels
Hyaluronic Acid
Crosslinking
Modulation
3 Citations (Scopus)

Overexpressed Calponin3 by Subsonic Vibration Induces Neural Differentiation of hUC-MSCs by Regulating the Ionotropic Glutamate Receptor

Kim, H. J., Kim, J. H., Song, Y. J., Seo, Y. K., Park, J. K. & Kim, C. W., 2015 Sep 28, In : Applied Biochemistry and Biotechnology. 177, 1, p. 48-62 15 p.

Research output: Contribution to journalArticle

Ionotropic Glutamate Receptors
Glutamate Receptors
Vibration
Proteins
Stem cells
16 Citations (Scopus)

Profilin 2 promotes migration, invasion, and stemness of HT29 human colorectal cancer stem cells

Kim, M. J., Lee, Y. S., Han, G. Y., Lee, H. N., Ahn, C. & Kim, C. W., 2015, In : Bioscience, Biotechnology and Biochemistry. 79, 9, p. 1438-1446 9 p.

Research output: Contribution to journalArticle

Profilins
Neoplastic Stem Cells
Stem cells
Colorectal Neoplasms
Epithelial-Mesenchymal Transition
8 Citations (Scopus)

Simple methods for tracking stem cells with <sup>64</sup>Cu-labeled DOTA-hexadecyl-benzoate

Kim, M. H., Woo, S. K., Kim, K. I., Lee, T. S., Kim, C. W., Kang, J. H., Kim, B. I., Lim, S. M., Lee, K. C. & Lee, Y. J., 2015 May 14, In : ACS Medicinal Chemistry Letters. 6, 5, p. 528-530 3 p.

Research output: Contribution to journalArticle

Benzoates
Stem cells
Stem Cells
Positron emission tomography
Positron-Emission Tomography
2014
6 Citations (Scopus)

Analysis of glycated serum proteins in type 2 diabetes patients with nephropathy

Kim, M. R., Yu, S. A., Kim, M. Y., Choi, K. M. & Kim, C. W., 2014 Jan 1, In : Biotechnology and Bioprocess Engineering. 19, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Blood Proteins
Diabetes Complications
Proteins
15 Citations (Scopus)

Effectsof extremely low frequency magnetic fieldson NGF induced neuronal differentiation of PC12 cells

Jung, I. S., Kim, H. J., Noh, R., Kim, S. C. & Kim, C. W., 2014 Jan 1, In : Bioelectromagnetics. 35, 7, p. 459-469 11 p.

Research output: Contribution to journalArticle

PC12 Cells
Nerve Growth Factor
Magnetic Fields
Neurites
Proteins
1 Citation (Scopus)

Exogenous rhTRX reduces lipid accumulation under LPS-induced inflammation

Han, G. Y., Lee, E. K., Park, H. W., Kim, H. J. & Kim, C. W., 2014 Jan 1, In : Experimental and Molecular Medicine. 46, 1, e71.

Research output: Contribution to journalArticle

Thioredoxins
Lipopolysaccharides
Inflammation
Lipids
Lipid Metabolism
2 Citations (Scopus)

Hydrogen peroxide as an effective disinfectant for Pasteurella multocida

Jung, I. S., Kim, H. J., Jung, W. Y. & Kim, C. W., 2014 Jan 1, In : Yonsei Medical Journal. 55, 4, p. 1152-1156 5 p.

Research output: Contribution to journalArticle

Pasteurella multocida
Disinfectants
Hydrogen Peroxide
Pasteurella Infections
2-Propanol