• 4559 Citations
  • 22 h-Index
19992019

Research output per year

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Research Output

2019

Growth signaling and longevity in mouse models

Kim, S. S. & Lee, C-K., 2019 Jan 1, In : BMB Reports. 52, 1, p. 70-85 16 p.

Research output: Contribution to journalShort survey

Open Access
2 Citations (Scopus)

Recent studies on anti-aging compounds with Saccharomyces cerevisiae as a model organism

Yalcin, G. & Lee, C. K., 2019, In : Translational Medicine of Aging. 3, p. 109-115 7 p.

Research output: Contribution to journalReview article

Open Access

Sulfate assimilation regulates hydrogen sulfide production independent of lifespan and reactive oxygen species under methionine restriction condition in yeast

Choi, K. M., Kim, S., Kim, S., Lee, H. M., Kaya, A., Chun, B. H., Lee, Y. K., Park, T. S., Lee, C-K., Eyun, S. I. & Lee, B. C., 2019 Jan 1, In : Aging. 11, 12, p. 4254-4273 20 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Leptin is a dose-dependent marker of caloric restriction in adipose tissues located in different parts of the mouse body

Hong, S. J., Kim, S. S., Lim, W., Song, G. & Lee, C-K., 2018 Jan 1, In : Molecular and Cellular Toxicology. 14, 1, p. 53-59 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

Caloric Restriction and Rapamycin Differentially Alter Energy Metabolism in Yeast

Choi, K. M., Hong, S. J., van Deursen, J. M., Kim, S., Kim, K. H. & Lee, C-K., 2017 Dec 12, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 73, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Caloric restriction-induced extension of chronological lifespan requires intact respiration in budding yeast

Kwon, Y. Y., Lee, S. K. & Lee, C-K., 2017 Apr 1, In : Molecules and Cells. 40, 4, p. 307-313 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Correlation between antioxidant enzyme activity, free iron content and lipid oxidation in four lines of Korean native chicken meat

Utama, D. T., Lee, S. G., Baek, K. H., Kim, H. K., Cho, C. Y., Lee, C-K. & Lee, S. K., 2016 Feb 1, In : Korean Journal for Food Science of Animal Resources. 36, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Whole-transcriptome analysis of mouse adipose tissue in response to short-term caloric restriction

Kim, S. S., Choi, K. M., Kim, S., Park, T., Cho, I. C., Lee, J. W. & Lee, C-K., 2016 Apr 1, In : Molecular Genetics and Genomics. 291, 2, p. 831-847 17 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2015

Cellular longevity of budding yeast during replicative and chronological aging

Choi, K. M. & Lee, C-K., 2015 Jan 1, Aging Mechanisms: Longevity, Metabolism, and Brain Aging. Springer Japan, p. 89-109 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Disruption of Snf3/Rgt2 glucose sensors decreases lifespan and caloric restriction effectiveness through Mth1/Std1 by adjusting mitochondrial efficiency in yeast

Choi, K. M., Kwon, Y. Y. & Lee, C-K., 2015 Jan 30, In : FEBS Letters. 589, 3, p. 349-357 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Mitochondrial efficiency-dependent viability of saccharomyces cerevisiae mutants carrying individual electron transport chain component deletions

Kwon, Y. Y., Choi, K. M., Cho, C. Y. & Lee, C-K., 2015 Nov 24, In : Molecules and Cells. 38, 12, p. 1054-1063 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Characterization of global gene expression during assurance of lifespan extension by caloric restriction in budding yeast

Choi, K. M., Kwon, Y. Y. & Lee, C. K., 2013, In : Experimental Gerontology. 48, 12, p. 1455-1468 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Enhancement of mitochondrial function correlates with the extension of lifespan by caloric restriction and caloric restriction mimetics in yeast

Choi, K. M., Lee, H. L., Kwon, Y. Y., Kang, M. S., Lee, S. K. & Lee, C. K., 2013 Nov 8, In : Biochemical and biophysical research communications. 441, 1, p. 236-242 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
15 Citations (Scopus)
2012

The lifespan of Korean eunuchs

Min, K. J., Lee, C. K. & Park, H. N., 2012 Sep 25, In : Current Biology. 22, 18, p. R792-R793

Research output: Contribution to journalLetter

88 Citations (Scopus)
2011
24 Citations (Scopus)

Differences in hepatic gene expression as a major distinguishing factor between Korean native pig and Yorkshire

Kim, S. S., Kim, S. R., Kim, J. R., Moon, J. K., Choi, B. H., Lee, J. W., Kim, K. S., Kim, T. H., Kim, H. J. & Lee, C. K., 2011, In : Bioscience, Biotechnology and Biochemistry. 75, 3, p. 451-458 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effects of oxypeucedanin on global gene expression and MAPK signaling pathway in mouse neuroblastoma neuro-2A cells

Choi, J. S., Shin, H. Y., Kwon, K. S., Shin, S., Choung, S. Y., Kwon, Y. S., Lee, J. W., Choi, B. H. & Lee, C. K., 2011, In : Planta Medica. 77, 13, p. 1512-1518 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

Investigation of porcine FABP3 and LEPR gene polymorphisms and mRNA expression for variation in intramuscular fat content

Li, X., Kim, S. W., Choi, J. S., Lee, Y. M., Lee, C. K., Choi, B. H., Kim, T. H., Choi, Y. I., Kim, J. J. & Kim, K. S., 2010 Dec, In : Molecular biology reports. 37, 8, p. 3931-3939 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Molecular characterization of a novel bacterial aryl acylamidase belonging to the amidase signature enzyme family.

Ko, H. J., Lee, E. W., Bang, W. G., Lee, C. K., Kim, K. H. & Choi, I. G., 2010 May, In : Molecules and cells. 29, 5, p. 485-492 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Quantitative gene expression analysis on chromosome 6 between Korean native pigs and Yorkshire breeds for fat deposition

Li, X., Lee, C. K., Choi, B. H., Kim, T. H., Kim, J. J. & Kim, K. S., 2010 Aug, In : Genes and Genomics. 32, 4, p. 385-393 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Time-dependently expressed markers and the characterization for premature senescence induced by ionizing radiation in MCF7

Kim, B. C., Han, N. K., Byun, H. O., Kim, S. S., Ahn, E. K., Chu, I. S., Leem, S. H., Lee, C. K. & Lee, J. S., 2010 Aug, In : Oncology reports. 24, 2, p. 395-403 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2009

Differentially expressed transcripts in adipose tissue between Korean native pig and Yorkshire breeds

Moon, J. K., Kim, K. S., Kim, J. J., Choi, B. H., Cho, B. W., Kim, T. H. & Lee, C. K., 2009 Feb, In : Animal Genetics. 40, 1, p. 115-118 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Transcriptional alteration of p53 related processes as a key factor for skeletal muscle characteristics in Sus scrofa

Kim, S. S., Kim, J. R., Moon, J. K., Choi, B. H., Kim, T. H., Kim, K. S., Kim, J. J. & Lee, C. K., 2009 Dec, In : Molecules and cells. 28, 6, p. 565-573 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2008

Characterization of beef transcripts correlated with tenderness and moisture

Kee, H. J., Park, E. W. & Lee, C. K., 2008 May 31, In : Molecules and cells. 25, 3, p. 428-437 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Differential expression of cytochrome p450 genes regulate the level of adipose arachidonic acid in Sus scrofa

Choi, K. M., Moon, J. K., Choi, S. H., Kim, K. S., Choi, Y. I., Kim, J. J. & Lee, C. K., 2008 Jul, In : Asian-Australasian Journal of Animal Sciences. 21, 7, p. 967-971 5 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Molecular changes in remote tissues induced by electro-acupuncture stimulation at acupoint ST36

Rho, S. W., Choi, G. S., Ko, E. J., Kim, S. K., Lee, Y. S., Lee, H. J., Hong, M. C., Shin, M. K., Min, B. I., Kee, H. J., Lee, C. K. & Bae, H. S., 2008 Apr 30, In : Molecules and cells. 25, 2, p. 178-183 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Molecular characteristics of the porcine DLK1 and MEG3 genes

Li, X. P., Do, K. T., Kim, J. J., Huang, J., Zhao, S. H., Lee, Y., Rothschild, M. F., Lee, C. K. & Kim, K. S., 2008 Apr, In : Animal Genetics. 39, 2, p. 189-192 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Transcriptional response according to strength of calorie restriction in Saccharomyces cerevisiae

Lee, Y. L. & Lee, C. K., 2008 Sep 30, In : Molecules and cells. 26, 3, p. 299-307 9 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2007

Detection of Mendelian and parent-of-origin quantitative trait loci in a cross between Korean native pig and Landrace I. Growth and body composition traits

Kim, E. H., Choi, B. H., Kim, K. S., Lee, C. K., Cho, B. W., Kim, T. H. & Kim, J. J., 2007 May, In : Asian-Australasian Journal of Animal Sciences. 20, 5, p. 669-676 8 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)
2006

Age- and vitamin E-induced changes in gene expression profiles of T cells

Hau, S. N., Adolfsson, O., Lee, C. K., Prolla, T. A., Ordovas, J. & Meydani, S. N., 2006 Nov 1, In : Journal of Immunology. 177, 9, p. 6052-6061 10 p.

Research output: Contribution to journalArticle

Open Access
54 Citations (Scopus)

Association of melanocortin 4 receptor (MC4R) and high mobility group AT-hook 1 (HMGA1) polymorphisms with pig growth and fat deposition traits

Kim, K. S., Lee, J. J., Shin, H. Y., Choi, B. H., Lee, C. K., Kim, J. J., Cho, B. W. & Kim, T. H., 2006 Aug, In : Animal Genetics. 37, 4, p. 419-421 3 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Cell cycle-specified fluctuation of nucleosome occupancy at gene promoters

Hogan, G. J., Lee, C. K. & Lieb, J. D., 2006, In : PLoS Genetics. 2, 9, p. 1433-1450 18 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection

Liu, X., Lee, C. K., Granek, J. A., Clarke, N. D. & Lieb, J. D., 2006 Dec, In : Genome Research. 16, 12, p. 1517-1528 12 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2004

Evidence for nucleosome depletion at active regulatory regions genome-wide

Lee, C. K., Shibata, Y., Rao, B., Strahl, B. D. & Lieb, J. D., 2004 Aug, In : Nature Genetics. 36, 8, p. 900-905 6 p.

Research output: Contribution to journalArticle

525 Citations (Scopus)

The impact of α-lipoic acid, coenzyme Q10, and caloric restriction on life span and gene expression patterns in mice

Lee, C. K., Pugh, T. D., Klopp, R. G., Edwards, J., Allison, D. B., Weindruch, R. & Prolla, T. A., 2004 Apr 15, In : Free Radical Biology and Medicine. 36, 8, p. 1043-1057 15 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Vitamin E and gene expression in immune cells

Han, S. N., Adolfsson, O., Lee, C. K., Prolla, T. A., Ordovas, J. & Meydani, S. N., 2004, In : Annals of the New York Academy of Sciences. 1031, p. 96-101 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2003

Classification of multiple cancer types by multicategory support vector machines using gene expression data

Lee, Y. & Lee, C. K., 2003 Jun 12, In : Bioinformatics. 19, 9, p. 1132-1139 8 p.

Research output: Contribution to journalArticle

231 Citations (Scopus)
2002

A mixture model approach for the analysis of microarray gene expression data

Allison, D. B., Gadbury, G. L., Heo, M., Fernández, J. R., Lee, C. K., Lee, C. K., Prolla, T. A., Weindruch, R. & Weindruch, R., 2002 Mar 28, In : Computational Statistics and Data Analysis. 38, 5, p. 1-20 20 p.

Research output: Contribution to journalArticle

262 Citations (Scopus)

Effects of caloric restriction on gene expression.

Weindruch, R., Kayo, T., Lee, C. K. & Prolla, T. A., 2002, In : Nestlé Nutrition workshop series. Clinical & performance programme.. 6, p. 17-28; discussion 28-2832

Research output: Contribution to journalReview article

5 Citations (Scopus)

Gene expression profiling of aging using DNA microarrays

Weindruch, R., Kayo, T., Lee, C. K. & Prolla, T. A., 2002, In : Mechanisms of Ageing and Development. 123, 2-3, p. 177-193 17 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts

Lee, C. K., Allison, D. B., Brand, J., Weindruch, R. & Prolla, T. A., 2002 Nov 12, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 23, p. 14988-14993 6 p.

Research output: Contribution to journalArticle

236 Citations (Scopus)
2001

Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice

Weindruch, R., Kayo, T., Lee, C. K. & Prolla, T. A., 2001, In : Journal of Nutrition. 131, 3, p. 918S-923S

Research output: Contribution to journalArticle

Open Access
211 Citations (Scopus)
2000

Gene-expression profile of the ageing brain in mice

Lee, C. K., Weindruch, R. & Prolla, T. A., 2000 Jul, In : Nature Genetics. 25, 3, p. 294-297 4 p.

Research output: Contribution to journalArticle

828 Citations (Scopus)

Use of urinary PAH metabolites to assess PAH exposure intervention among coke oven workers

Cho, S. H., Kang, D., Kang, J. W., Ju, Y. S., Sung, J., Lee, C. K., Lee, S. K., Lee, Y. S. & Strickland, P. T., 2000 May, In : Journal of Occupational Health. 42, 3, p. 138-143 6 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
1999

Comparison of three analytical methods for 1-hydroxypyrene glucuronide in urine after non-occupational exposure to polycyclic aromatic hydrocarbons

Lee, C. K., Cho, S. H., Kang, J. W., Lee, S. J., Ju, Y. S., Sung, J., Strickland, P. T. & Kang, D., 1999 Sep 5, In : Toxicology Letters. 108, 2-3, p. 209-215 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Gene expression profile of aging and its retardation by caloric restriction

Lee, C. K., Klopp, R. G., Weindruch, R. & Prolla, T. A., 1999 Aug 27, In : Science. 285, 5432, p. 1390-1393 4 p.

Research output: Contribution to journalArticle

1216 Citations (Scopus)

Variations in urinary 1-hydroxypyrene glucuronide in relation to smoking and the modification effects of GSTM1 and GSTT1

Hong, Y. C., Leem, J. H., Park, H. S., Lee, K. H., Lee, S. J., Lee, C. K. & Kang, D., 1999 Sep 5, In : Toxicology Letters. 108, 2-3, p. 217-223 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)