• 2555 Citations
  • 28 h-Index
1992 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 2555 Citations
  • 28 h-Index
  • 76 Article
  • 2 Patent
  • 1 Review article
2020

Hepatitis C virus p7 induces membrane permeabilization by interacting with phosphatidylserine

Lee, H. R., Lee, G. Y., You, D. G., Kim, H. K. & Do Yoo, Y., 2020 Feb, In : International journal of molecular sciences. 21, 3, 897.

Research output: Contribution to journalArticle

Open Access
2019

Hepatitis B virus X protein induces size-selective membrane permeabilization through interaction with cardiolipin

You, D. G., Cho, Y. Y., Lee, H. R., Lee, J. H., Yu, S. J., Yoon, J. H., Yoo, Y. D., Kim, Y. J. & Lee, G. Y., 2019 Apr 1, In : Biochimica et Biophysica Acta - Biomembranes. 1861, 4, p. 729-737 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

A direct role for hepatitis B virus X protein in inducing mitochondrial membrane permeabilization

Lee, H. R., Cho, Y. Y., Lee, G. Y., You, D. G., Yoo, Y. D. & Kim, Y. J., 2018 Jan 1, (Accepted/In press) In : Journal of Viral Hepatitis.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A novel anti-cancer role of β-apopicropodophyllin against non-small cell lung cancer cells

Kim, J. Y., Cho, J. H., Choi, J. R., Shin, H. J., Song, J. Y., Hwang, S. G., Um, H. D., Yoo, Y. D., Kim, J. & Park, J. K., 2018 Oct 15, In : Toxicology and Applied Pharmacology. 357, p. 39-49 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Overexpression of romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients

Kim, H. J., Jo, M. J., Kim, B. R., Kim, J. L., Jeong, Y. A., Na, Y. J., Park, S. H., Lee, S. Y., Lee, D. H., Kim, B-H., Yoo, Y. D. & Oh, S. C., 2018 Jan 1, In : OncoTargets and Therapy. 11, p. 4233-4246 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Romo1 is a mitochondrial nonselective cation channel with viroporin-like characteristics

Lee, G. Y., You, D. G., Lee, H. R., Hwang, S. W., Lee, C. & Yoo, Y. D., 2018 Jun 1, In : Journal of Cell Biology. 217, 6, p. 2059-2071 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2017

Hepatitis C virus p7 induces mitochondrial depolarization of isolated liver mitochondria

You, D. G., Lee, H. R., Kim, W-K., Kim, H. J., Lee, G. Y. & Yoo, Y. D., 2017 Dec 1, In : Molecular Medicine Reports. 16, 6, p. 9533-9538 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Reactive oxygen species modulator-1 (Romo1) predicts unfavorable prognosis in colorectal cancer patients

Kim, H. J., Jo, M. J., Kim, B. R., Kim, J. L., Jeong, Y. A., Na, Y. J., Park, S. H., Lee, S. Y., Lee, D. H., Lee, H. S., Kim, B-H., Lee, S. I., Min, B. W., Yoo, Y. D. & Oh, S. C., 2017 May 1, In : PLoS One. 12, 5, e0176834.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The mitochondrial hinge protein, UQCRH, is a novel prognostic factor for hepatocellular carcinoma

Park, E. R., Kim, S. B., Lee, J. S., Kim, Y. H., Lee, D. H., Cho, E. H., Park, S. H., Han, C. J., Kim, B. Y., Choi, D. W., Yoo, Y. D., Yu, A., Lee, J. W., Jang, J. J., Park, Y. N., Suh, K. S. & Lee, K. H., 2017 Apr 1, In : Cancer Medicine. 6, 4, p. 749-760 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2016

Hepatitis C virus p7 mediates membrane-to-membrane adhesion

Lee, G. Y., Lee, S., Lee, H. R. & Yoo, Y. D., 2016 Sep 1, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1861, 9, p. 1096-1101 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Simple and biocompatible ion beam micropatterning of a cell-repellent polymer on cell-adhesive surfaces to manipulate cell adhesion

Hwang, I. T., Jung, C. H., Jung, C. H., Choi, J. H., Shin, K. & Yoo, Y. D., 2016 Feb 1, In : Journal of Biomedical Nanotechnology. 12, 2, p. 387-393 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015
11 Citations (Scopus)

Romo1 and the NF-κB pathway are involved in oxidative stress-induced tumor cell invasion

Lee, S., Park, Y. H., Chung, J. S. & Yoo, Y. D., 2015 May 1, In : International Journal of Oncology. 46, 5, p. 2021-2028 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2014

Constitutive NF-κB activation and tumor-growth promotion by Romo1-mediated reactive oxygen species production

Chung, J. S., Lee, S. & Yoo, Y. D., 2014 Aug 8, In : Biochemical and Biophysical Research Communications. 450, 4, p. 1656-1661 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Romo1 expression contributes to oxidative stress-induced death of lung epithelial cells

Shin, J. A., Chung, J. S., Cho, S. H., Kim, H. J. & Yoo, Y. D., 2013 Sep 20, In : Biochemical and Biophysical Research Communications. 439, 2, p. 315-320 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2012

ANTIBODY AGAINST ROMO1, HYBRIDOMA PRODUCING THE SAME AND USES THEREOF

Yoo, Y. D., 2012 Apr 26, Patent No. 10-1142418

Research output: Patent

Integrated analysis of prognostic gene expression profiles from hepatitis B virus-positive hepatocellular carcinoma and adjacent liver tissue

Kim, B. Y., Suh, K. S., Lee, J. G., Woo, S. R., Park, I. C., Park, S. H., Han, C. J., Kim, S. B., Jeong, S. H., Yeom, Y. I., Yang, S. J., Kim, C. M., Cho, S. J., Yoo, Y. D., Cho, M. H., Jang, J. J., Choi, D. W. & Lee, K. H., 2012 Jul 1, In : Annals of Surgical Oncology. 19, SUPPL. 3

Research output: Contribution to journalArticle

7 Citations (Scopus)

Overexpression of Romo1 promotes production of reactive oxygen species and invasiveness of hepatic tumor cells

Chung, J. S., Park, S., Park, S. H., Park, E. R., Cha, P. H., Kim, B. Y., Chung, Y. M., Woo, S. R., Han, C. J., Kim, S. B., Suh, K. S., Jang, J. J., Lee, K., Choi, D. W., Lee, S., Lee, G. Y., Hahm, K. B., Shin, J. A., Kim, B. S., Noh, K. H. & 3 others, Kim, T. W., Lee, K. H. & Yoo, Y. D., 2012 Oct 1, In : Gastroenterology. 143, 4

Research output: Contribution to journalArticle

38 Citations (Scopus)
2011

Bcl-XL prevents serum deprivation-induced oxidative stress mediated by Romo1

Lee, S. B., Kim, H. J., Shin, J., Kang, S. T., Kang, S. & Yoo, Y. D. O., 2011 May 1, In : Oncology reports. 25, 5, p. 1337-1342 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Human feeder cells can support the undifferentiated growth of human and mouse embryonic stem cells using their own basic fibroblast growth factors.

Park, Y., Kim, J. H., Lee, S. J., Choi, I. Y., Park, S. J., Lee, S. R., Sung, H. J., Yoo, Y. D., Geum, D. H., Choi, C. W., Kim, S. H. & Kim, B. S., 2011 Nov 1, In : Stem Cells and Development. 20, 11, p. 1901-1910 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

RASSF1A suppresses the activated K-Ras-induced oxidative DNA damage

Park, S. H., Kim, J. J., Chung, J. S., Lee, S. R., Lee, G. Y., Kim, H. J. & Yoo, Y. D., 2011 Apr 29, In : Biochemical and Biophysical Research Communications. 408, 1, p. 149-153 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Regulation of reactive oxygen species generation in cell signaling

Bae, Y. S., Oh, H., Rhee, S. G. & Yoo, Y. D., 2011 Dec 1, In : Molecules and cells. 32, 6, p. 491-509 19 p.

Research output: Contribution to journalReview article

276 Citations (Scopus)

Romo1 is a negative-feedback regulator of Myc

Lee, S. B., Kim, J. J., Chung, J. S., Lee, M. S., Lee, K. H., Kim, B. S. & Yoo, Y. D., 2011 Jul 15, In : Journal of Cell Science. 124, 14, p. 2512-2400

Research output: Contribution to journalArticle

Romo1 is a negative-feedback regulator of Myc

Lee, S. B., Kim, J. J., Chung, J. S., Lee, M. S., Lee, K. H., Kim, B. S., Tansey, W. P. & Yoo, Y. D., 2011 Jun 1, In : Journal of Cell Science. 124, 11, p. 1911-1924 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2010

Clonal cell populations unresponsive to radiosensitization induced by telomerase inhibition

Ju, Y. J., Shin, H. J., Park, J. E., Juhn, K. M., Woo, S. R., Kim, H. Y., Han, Y. H., Hwang, S. G., Hong, S. H., Kang, C. M., Yoo, Y. D., Park, W. B., Cho, M. H., Park, G. H. & Lee, K. H., 2010 Nov 12, In : Biochemical and biophysical research communications. 402, 2, p. 198-202 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB

Park, J. K., Park, S. H., So, K., Bae, I. H., Yoo, Y. D. & Um, H. D., 2010 Jan 1, In : International Journal of Oncology. 36, 1, p. 181-192 12 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Serum deprivation-induced reactive oxygen species production is mediated by Romo1

Lee, S. B., Kim, J. J., Kim, T. W., Kim, B. S., Lee, M. S. & Yoo, Y. D., 2010 Feb 1, In : Apoptosis. 15, 2, p. 204-218 15 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

The efficacy of human placenta as a source of the universal feeder in human and mouse pluripotent stem cell culture

Park, Y., Lee, S. J., Choi, I. Y., Lee, S. R., Sung, H. J., Kim, J-H., Yoo, Y. D., Geum, D., Kim, S. H. & Kim, B. S., 2010 Jun 1, In : Cellular Reprogramming. 12, 3, p. 315-328 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL

Kim, J. J., Lee, S. B., Park, J. K. & Yoo, Y. D., 2010 Sep 1, In : Cell Death and Differentiation. 17, 9, p. 1420-1434 15 p.

Research output: Contribution to journalArticle

167 Citations (Scopus)
22 Citations (Scopus)
2009

Enhancement of dendritic cell-based vaccine potency by anti-apoptotic siRNAs targeting key pro-apoptotic proteins in cytotoxic CD8+ T cell-mediated cell death

Kim, J. H., Kang, T. H., Noh, K. H., Bae, H. C., Kim, S. H., Yoo, Y. D., Seong, S. Y. & Kim, T. W., 2009 Jan 29, In : Immunology Letters. 122, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Gefitinib circumvents hypoxia-induced drug resistance by the modulation of HIF-1α

Rho, J. K., Choi, Y. J., Lee, J. K., Ryoo, B. Y., Na, I. II., Yang, S. H., Kim, C. H., Yoo, Y. D. & Lee, J. C., 2009 Apr 23, In : Oncology reports. 21, 3, p. 801-807 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Mitochondrial reactive oxygen species originating from Romo1 exert an important role in normal cell cycle progression by regulating p27Kip1 expression

Chung, J. S., Lee, S. B., Park, S. H., Kang, S. T., Na, A. R., Chang, T. S., Kim, H. J. & Yoo, Y. D., 2009 Jul 27, In : Free Radical Research. 43, 8, p. 729-737 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

The role of MET activation in determining the sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors

Rho, J. K., Choi, Y. J., Lee, J. K., Ryoo, B. Y., Na, I. I., Yang, S. H., Lee, S. S., Kim, C. H., Yoo, Y. D. & Lee, J. C., 2009 Oct 1, In : Molecular Cancer Research. 7, 10, p. 1736-1743 8 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2008

A critical role for Romo1-derived ROS in cell proliferation

Na, A. R., Chung, Y. M., Lee, S. B., Park, S. H., Lee, M. S. & Yoo, Y. D., 2008 May 2, In : Biochemical and biophysical research communications. 369, 2, p. 672-678 7 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

NDRG2 gene expression in B16F10 melanoma cells restrains melanogenesis via inhibition of Mitf expression

Kim, A., Yang, Y., Lee, M. S., Yoo, Y. D., Lee, H. G. & Lim, J. S., 2008 Dec 1, In : Pigment Cell and Melanoma Research. 21, 6, p. 653-664 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Replicative senescence induced by romo1-derived reactive oxygen species

Young, M. C., Seung, B. L., Hyung, J. K., Seon, H. P., Jung, J. K., Jin, S. C. & Yoo, Y. D., 2008 Nov 28, In : Journal of Biological Chemistry. 283, 48, p. 33763-33771 9 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2007

CSSP2: An improved method for predicting contact-dependent secondary structure propensity

Yoon, S., Welsh, W. J., Jung, H. & Yoo, Y. D., 2007 Oct 1, In : Computational Biology and Chemistry. 31, 5-6, p. 373-377 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Drug resistance to 5-FU linked to reactive oxygen species modulator 1

Hwang, I. T., Chung, Y. M., Kim, J. J., Chung, J. S., Kim, B. S., Kim, H. J., Kim, J. S. & Yoo, Y. D., 2007 Jul 27, In : Biochemical and Biophysical Research Communications. 359, 2, p. 304-310 7 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Human placenta-derived feeders support prolonged undifferentiated propagation of a human embryonic stem cell line, SNUhES3: Comparison with human bone marrow-derived feeders

Seok, J. K., Chang, H. S., Sung, H. J., Yoo, Y. D., Geum, D., Sun, H. P., Ji, H. Y., Jee, H. O., Hye, J. S., Sun, H. K., Kim, J. S. & Kim, B. S., 2007 Jun 1, In : Stem Cells and Development. 16, 3, p. 421-428 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The activity of 2′-benzoyloxycinnamaldehyde against drug-resistant cancer cell lines

Young, M. C., Young, D. Y., Jun, S. K., Chang, Y. L. & Hyung, J. K., 2007 Aug 1, In : Journal of Chemotherapy. 19, 4, p. 428-437 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2006

A novel protein, Romo1, induces ROS production in the mitochondria

Chung, Y. M., Kim, J. S. & Yoo, Y. D., 2006 Sep 1, In : Biochemical and Biophysical Research Communications. 347, 3, p. 649-655 7 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

ICAM-3-induced cancer cell proliferation through the PI3K/Akt pathway

Kim, Y. G., Kim, M. J., Lim, J. S., Lee, M. S., Kim, J. S. & Yoo, Y. D., 2006 Jul 28, In : Cancer letters. 239, 1, p. 103-110 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

RASSF1A suppresses oncogenic H-Ras-induced c-Jun N-terminal kinase activation

Yoo, Y. A., Na, A. R., Lee, M. S., Yoon, S., Kim, J. S. & Yoo, Y. D., 2006 Dec 1, In : International journal of oncology. 29, 6, p. 1541-1547 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Single nucleotide polymorphisms of the TGFB1 gene and lung cancer risk in a Korean population

Park, K. H., Lo Han, S. G., Whang, Y. M., Lee, H. J., Yoo, Y. D., Lee, J. W., Shin, S. W. & Kim, Y. H., 2006 Aug 1, In : Cancer Genetics and Cytogenetics. 169, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2005

CDK2/4 regulate retinoic acid-induced G1 arrest in hepatocellular carcinoma cells

Jung, H. Y., Park, S. H., Yoo, Y. D., Kim, J. S. & Kim, Y. H., 2005 Mar 1, In : Hepatology Research. 31, 3, p. 143-152 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
11 Citations (Scopus)