ε-Amino acids based on bicyclic skeleton: bicyclo[3.3.0]octane-5-amino-1-carboxylic acids

Sung Jin Yeo, Kyung Seok Jeong, Hogyu Han, Jaheon Kim, Nakcheol Jeong

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Tsc-protected ε-amino acids, bicyclo[3.3.0]octane-5-amino-1-carboxylic acids (1), ready to use in the solid-phase synthesis, are prepared from 4,4-diethylcarboxylic bicyclo[3.3.0]oct-2-enone (3), which is available in bulk from 2 through the catalytic Pauson-Khand reaction.

Original languageEnglish
Pages (from-to)7389-7393
Number of pages5
JournalTetrahedron Letters
Volume47
Issue number41
DOIs
Publication statusPublished - 2006 Oct 9

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Solid-Phase Synthesis Techniques
Carboxylic Acids
Skeleton
Amino Acids
octane

Keywords

  • ε-Amino acid
  • Bicyclic amino acid
  • Pauson-Khand reaction
  • Solid phase synthesis
  • Tsc amine-protecting group
  • Unnatural amino acid

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

ε-Amino acids based on bicyclic skeleton : bicyclo[3.3.0]octane-5-amino-1-carboxylic acids. / Yeo, Sung Jin; Jeong, Kyung Seok; Han, Hogyu; Kim, Jaheon; Jeong, Nakcheol.

In: Tetrahedron Letters, Vol. 47, No. 41, 09.10.2006, p. 7389-7393.

Research output: Contribution to journalArticle

Yeo, Sung Jin ; Jeong, Kyung Seok ; Han, Hogyu ; Kim, Jaheon ; Jeong, Nakcheol. / ε-Amino acids based on bicyclic skeleton : bicyclo[3.3.0]octane-5-amino-1-carboxylic acids. In: Tetrahedron Letters. 2006 ; Vol. 47, No. 41. pp. 7389-7393.
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