ε-Amino acids based on bicyclic skeleton: bicyclo[3.3.0]octane-5-amino-1-carboxylic acids

Sung Jin Yeo; Kyung Seok Jeong; Hogyu Han; Jaheon Kim; Nakcheol Jeong

doi:10.1016/j.tetlet.2006.07.137

ε-Amino acids based on bicyclic skeleton: bicyclo[3.3.0]octane-5-amino-1-carboxylic acids

Sung Jin Yeo, Kyung Seok Jeong, Hogyu Han, Jaheon Kim, Nakcheol Jeong

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

Tsc-protected ε-amino acids, bicyclo[3.3.0]octane-5-amino-1-carboxylic acids (1), ready to use in the solid-phase synthesis, are prepared from 4,4-diethylcarboxylic bicyclo[3.3.0]oct-2-enone (3), which is available in bulk from 2 through the catalytic Pauson-Khand reaction.

Original language	English
Pages (from-to)	7389-7393
Number of pages	5
Journal	Tetrahedron Letters
Volume	47
Issue number	41
DOIs	https://doi.org/10.1016/j.tetlet.2006.07.137
Publication status	Published - 2006 Oct 9

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Keywords

ε-Amino acid
Bicyclic amino acid
Pauson-Khand reaction
Solid phase synthesis
Tsc amine-protecting group
Unnatural amino acid

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Drug Discovery

Cite this

Yeo, S. J., Jeong, K. S., Han, H., Kim, J., & Jeong, N. (2006). ε-Amino acids based on bicyclic skeleton: bicyclo[3.3.0]octane-5-amino-1-carboxylic acids. Tetrahedron Letters, 47(41), 7389-7393. https://doi.org/10.1016/j.tetlet.2006.07.137

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AU - Han, Hogyu

AU - Kim, Jaheon

AU - Jeong, Nakcheol

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Access to Document

10.1016/j.tetlet.2006.07.137