25-Hydroxyvitamin D insufficiency is associated with cardiometabolic risk in Korean adolescents: the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES)

Ga E.un Nam, Do-Hoon Kim, Kyung-Hwan Cho, Yong G.yu Park, Kyung D.o. Han, Seon Mee Kim, Seung H.wan Lee, Byung J.oon Ko, Min Ja Kim

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

OBJECTIVE: Vitamin D insufficiency is known to be related to cardiometabolic disorders; however, the associations among serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome and cardiometabolic risk factors in children and adolescents have not yet been clearly delineated. For this reason, we investigated the relationship among serum 25(OH)D concentration and metabolic syndrome and cardiometabolic risk factors among Korean adolescents.

DESIGN: We performed a cross-sectional analysis and used hierarchical multivariate logistic regression analysis models to adjust for confounding variables.

SETTING: We used the data gathered during the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES).

SUBJECTS: Our subjects included 1504 Korean adolescents aged 12-18 years who participated in the KNHANES.

RESULTS: Vitamin D insufficiency, defined as 25(OH)D concentration <50 nmol/l, was found in 75·3% of Korean adolescents and was associated with an increased risk of the prevalence of metabolic syndrome. Waist circumference and BMI were the most closely correlated cardiometabolic components of metabolic syndrome according to serum 25(OH)D status, but no significant relationship was found between serum 25(OH)D concentration and insulin resistance or for the risks for high blood pressure, hyperglycaemia, reduced HDL-cholesterol or hypertriacylglycerolaemia, with or without adjustment for confounding variables.

CONCLUSIONS: Low serum 25(OH)D concentration appears to be associated with several cardiometabolic risk factors and an increased risk of the prevalence of metabolic syndrome in Korean adolescents.

Original languageEnglish
Pages (from-to)186-194
Number of pages9
JournalPublic Health Nutrition
Volume17
Issue number1
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Nutrition Surveys
Korea
Serum
Confounding Factors (Epidemiology)
Vitamin D
Waist Circumference
Hyperglycemia
HDL Cholesterol
Insulin Resistance
Cross-Sectional Studies
Logistic Models
Regression Analysis
25-hydroxyvitamin D
Hypertension

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Public Health, Environmental and Occupational Health

Cite this

25-Hydroxyvitamin D insufficiency is associated with cardiometabolic risk in Korean adolescents : the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES). / Nam, Ga E.un; Kim, Do-Hoon; Cho, Kyung-Hwan; Park, Yong G.yu; Han, Kyung D.o.; Kim, Seon Mee; Lee, Seung H.wan; Ko, Byung J.oon; Kim, Min Ja.

In: Public Health Nutrition, Vol. 17, No. 1, 01.01.2014, p. 186-194.

Research output: Contribution to journalArticle

@article{e8975db3601649daa3884e9f8f9c54c6,
title = "25-Hydroxyvitamin D insufficiency is associated with cardiometabolic risk in Korean adolescents: the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES)",
abstract = "OBJECTIVE: Vitamin D insufficiency is known to be related to cardiometabolic disorders; however, the associations among serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome and cardiometabolic risk factors in children and adolescents have not yet been clearly delineated. For this reason, we investigated the relationship among serum 25(OH)D concentration and metabolic syndrome and cardiometabolic risk factors among Korean adolescents.DESIGN: We performed a cross-sectional analysis and used hierarchical multivariate logistic regression analysis models to adjust for confounding variables.SETTING: We used the data gathered during the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES).SUBJECTS: Our subjects included 1504 Korean adolescents aged 12-18 years who participated in the KNHANES.RESULTS: Vitamin D insufficiency, defined as 25(OH)D concentration <50 nmol/l, was found in 75·3{\%} of Korean adolescents and was associated with an increased risk of the prevalence of metabolic syndrome. Waist circumference and BMI were the most closely correlated cardiometabolic components of metabolic syndrome according to serum 25(OH)D status, but no significant relationship was found between serum 25(OH)D concentration and insulin resistance or for the risks for high blood pressure, hyperglycaemia, reduced HDL-cholesterol or hypertriacylglycerolaemia, with or without adjustment for confounding variables.CONCLUSIONS: Low serum 25(OH)D concentration appears to be associated with several cardiometabolic risk factors and an increased risk of the prevalence of metabolic syndrome in Korean adolescents.",
author = "Nam, {Ga E.un} and Do-Hoon Kim and Kyung-Hwan Cho and Park, {Yong G.yu} and Han, {Kyung D.o.} and Kim, {Seon Mee} and Lee, {Seung H.wan} and Ko, {Byung J.oon} and Kim, {Min Ja}",
year = "2014",
month = "1",
day = "1",
doi = "10.1017/S1368980012004855",
language = "English",
volume = "17",
pages = "186--194",
journal = "Public Health Nutrition",
issn = "1368-9800",
publisher = "Cambridge University Press",
number = "1",

}

TY - JOUR

T1 - 25-Hydroxyvitamin D insufficiency is associated with cardiometabolic risk in Korean adolescents

T2 - the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES)

AU - Nam, Ga E.un

AU - Kim, Do-Hoon

AU - Cho, Kyung-Hwan

AU - Park, Yong G.yu

AU - Han, Kyung D.o.

AU - Kim, Seon Mee

AU - Lee, Seung H.wan

AU - Ko, Byung J.oon

AU - Kim, Min Ja

PY - 2014/1/1

Y1 - 2014/1/1

N2 - OBJECTIVE: Vitamin D insufficiency is known to be related to cardiometabolic disorders; however, the associations among serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome and cardiometabolic risk factors in children and adolescents have not yet been clearly delineated. For this reason, we investigated the relationship among serum 25(OH)D concentration and metabolic syndrome and cardiometabolic risk factors among Korean adolescents.DESIGN: We performed a cross-sectional analysis and used hierarchical multivariate logistic regression analysis models to adjust for confounding variables.SETTING: We used the data gathered during the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES).SUBJECTS: Our subjects included 1504 Korean adolescents aged 12-18 years who participated in the KNHANES.RESULTS: Vitamin D insufficiency, defined as 25(OH)D concentration <50 nmol/l, was found in 75·3% of Korean adolescents and was associated with an increased risk of the prevalence of metabolic syndrome. Waist circumference and BMI were the most closely correlated cardiometabolic components of metabolic syndrome according to serum 25(OH)D status, but no significant relationship was found between serum 25(OH)D concentration and insulin resistance or for the risks for high blood pressure, hyperglycaemia, reduced HDL-cholesterol or hypertriacylglycerolaemia, with or without adjustment for confounding variables.CONCLUSIONS: Low serum 25(OH)D concentration appears to be associated with several cardiometabolic risk factors and an increased risk of the prevalence of metabolic syndrome in Korean adolescents.

AB - OBJECTIVE: Vitamin D insufficiency is known to be related to cardiometabolic disorders; however, the associations among serum 25-hydroxyvitamin D (25(OH)D) concentration and metabolic syndrome and cardiometabolic risk factors in children and adolescents have not yet been clearly delineated. For this reason, we investigated the relationship among serum 25(OH)D concentration and metabolic syndrome and cardiometabolic risk factors among Korean adolescents.DESIGN: We performed a cross-sectional analysis and used hierarchical multivariate logistic regression analysis models to adjust for confounding variables.SETTING: We used the data gathered during the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES).SUBJECTS: Our subjects included 1504 Korean adolescents aged 12-18 years who participated in the KNHANES.RESULTS: Vitamin D insufficiency, defined as 25(OH)D concentration <50 nmol/l, was found in 75·3% of Korean adolescents and was associated with an increased risk of the prevalence of metabolic syndrome. Waist circumference and BMI were the most closely correlated cardiometabolic components of metabolic syndrome according to serum 25(OH)D status, but no significant relationship was found between serum 25(OH)D concentration and insulin resistance or for the risks for high blood pressure, hyperglycaemia, reduced HDL-cholesterol or hypertriacylglycerolaemia, with or without adjustment for confounding variables.CONCLUSIONS: Low serum 25(OH)D concentration appears to be associated with several cardiometabolic risk factors and an increased risk of the prevalence of metabolic syndrome in Korean adolescents.

UR - http://www.scopus.com/inward/record.url?scp=84897450042&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897450042&partnerID=8YFLogxK

U2 - 10.1017/S1368980012004855

DO - 10.1017/S1368980012004855

M3 - Article

C2 - 23168294

AN - SCOPUS:84897450042

VL - 17

SP - 186

EP - 194

JO - Public Health Nutrition

JF - Public Health Nutrition

SN - 1368-9800

IS - 1

ER -