3-dimensional in-vitro human nasal mucous membrane with glands

Kyuhwan Na, Mingyu Lee, Hyun Woo Shin, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The microfluidic epithelial models to mimic microenvironment physiologically has potential to be a useful tool for drug screening and pathophysiologic researches. Although a number of researches have demonstrated in-vitro nasal epithelial models, only few studies showed complicated nasal mucous membrane models. Here, we introduced a new 3-dimmensional (3D) in-vitro human nasal mucosa model with glands by optimizing culture conditions such as media, air-interfacing, hydrogels and type of cells in micro-scale. The similarity between in-vivo nasal mucous membrane and our invitro model suggest its utilization as a reliable research model for nasal disease models.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages503-504
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 2016 Oct 92016 Oct 13

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period16/10/916/10/13

    Fingerprint

Keywords

  • 3-dimensional
  • Glands
  • Nasal epithelial model
  • Nasal mucosa

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Na, K., Lee, M., Shin, H. W., & Chung, S. (2016). 3-dimensional in-vitro human nasal mucous membrane with glands. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 503-504). Chemical and Biological Microsystems Society.