3d culture strategy to enhance hair inductive potential of human hair follicle derived dermal papilla cells

Seongkyun Choi, Jinchul Ahn, Ji Hun Yang, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The dermal papilla is a cluster of specially aggregated mesenchymal cells located beneath the hair follicle(HF) which plays a crucial role in hair morphogenesis and cycle. Therefore, dermal papilla(DP) is a very important source for researches on hair. However, isolated DP cells(DPCs) easily lost their hair inductive potential within several subcultures. Here, we suggest a simple culture method for DPCs in 3D using a concave type plate and maintain hair inductive potential, without any treatment. Alkaline phosphatase (ALP) were examined to investigate 3D cultured DP spheroids and can sustain the hair inductive potential, which was rarely observed in 2D culture.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages1498-1499
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 2019 Oct 272019 Oct 31

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
CountrySwitzerland
CityBasel
Period19/10/2719/10/31

Keywords

  • 3D culture
  • Dermal Papilla
  • Hair follicle
  • Hair inductive potential

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

Fingerprint Dive into the research topics of '3d culture strategy to enhance hair inductive potential of human hair follicle derived dermal papilla cells'. Together they form a unique fingerprint.

Cite this