3D in vitro model of neural stem cell-vascular niche

Yoojin Shin, Sewoon Han, Kisuk Yang, Seung Woo Cho, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Neural stem cells reside in a specialized vascular microenvironment that is termed "neural stem cell niche", Brain vessels are the most important element in the NSC niche and paly an important role in balancing NSC's maintenance and differentiation in order to maintain tissue homeostasis. In this study, we developed reconstituted 3D in vitro neural stem cell-vascular niche that consists of extracellular matrix (ECM) and brain vessels to study cellular interaction between brain vessels and NSCs in a physiologically relevant microenvironment.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages545-547
Number of pages3
Volume1
ISBN (Print)9781632666246
Publication statusPublished - 2013 Jan 1
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: 2013 Oct 272013 Oct 31

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period13/10/2713/10/31

    Fingerprint

ASJC Scopus subject areas

  • Bioengineering

Cite this

Shin, Y., Han, S., Yang, K., Cho, S. W., & Chung, S. (2013). 3D in vitro model of neural stem cell-vascular niche. In 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 (Vol. 1, pp. 545-547). Chemical and Biological Microsystems Society.