TY - GEN
T1 - 4D image warping for measurement of longitudinal brain changes
AU - Shen, Dinggang
PY - 2004
Y1 - 2004
N2 - This paper presents a method for robustly measuring temporal morphological brain changes, by means of a 4D image warping mechanism. Longitudinal stability is achieved by considering all temporal MR images of an individual simultaneously in image warping, rather than by individually warping a 3D template to an individual, or by warping the images of one time-point to those of another time-point. Moreover, image features that are consistently recognized in all time-points guide the warping procedure, whereas spurious features that appear inconsistently at different time-points are eliminated. This deformation strategy significantly improves robustness in detecting anatomical correspondences, thereby producing smooth and accurate estimations of longitudinal changes. The experimental results show the significant improvement of 4D warping method over our previous 3D warping method in measuring subtle longitudinal changes of brain structures.
AB - This paper presents a method for robustly measuring temporal morphological brain changes, by means of a 4D image warping mechanism. Longitudinal stability is achieved by considering all temporal MR images of an individual simultaneously in image warping, rather than by individually warping a 3D template to an individual, or by warping the images of one time-point to those of another time-point. Moreover, image features that are consistently recognized in all time-points guide the warping procedure, whereas spurious features that appear inconsistently at different time-points are eliminated. This deformation strategy significantly improves robustness in detecting anatomical correspondences, thereby producing smooth and accurate estimations of longitudinal changes. The experimental results show the significant improvement of 4D warping method over our previous 3D warping method in measuring subtle longitudinal changes of brain structures.
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M3 - Conference contribution
AN - SCOPUS:17144394875
SN - 0780383885
SN - 9780780383883
T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
SP - 904
EP - 907
BT - 2004 2nd IEEE International Symposium on Biomedical Imaging
T2 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Y2 - 15 April 2004 through 18 April 2004
ER -