6-Pentyl-α-pyrone as an anti-sapstain compound produced by Trichoderma gamsii KUC1747 inhibits the germination of ophiostomatoid fungi

Joo Hyun Hong, Jaejung Lee, Mihee Min, Seung Mok Ryu, Dongho Lee, Gyu Hyeok Kim, Jae-Jin Kim

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The capability of Trichoderma gamsii to biologically control sapstain fungi has been investigated. Six ophiostomatoids, including Ophiostoma floccosum, O. piceae, O. piliferum, O. ips, Grosmannia koreana, and G. piceaperda, were inhibited by the extracts of T. gamsii. Of the various cultivation periods, 7 days of T. gamsii cultivation produced antifungal compounds most efficiently. The crude extracts of T. gamsii inhibited O. ips, G. koreana, and G. piceaperda by over 99%. The crude extracts of T. gamsii were isolated, and the compounds were purified by thin layer chromatography (TLC), open column chromatography, ultra-performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry (UPLC-QToF-MS) and NMR spectroscopy. The active fractions were separated based on the degree of T. gamsii antifungal activity. The compound 6-pentyl-α-pyrone (6PAP) was evaluated as a biological control agent for sapstain fungi.

Original languageEnglish
Pages (from-to)769-774
Number of pages6
JournalHolzforschung
Volume68
Issue number7
DOIs
Publication statusPublished - 2014 Jan 1

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Pyrones
Fungi
Complex Mixtures
Biological Control Agents
Thin layer chromatography
Column chromatography
Liquid chromatography
Nuclear magnetic resonance spectroscopy
Mass spectrometry

Keywords

  • 6-pentyl-α-pyrone
  • biological control agents
  • fungal extracts
  • ophiostomatoid fungi
  • Trichoderma gamsii

ASJC Scopus subject areas

  • Biomaterials

Cite this

6-Pentyl-α-pyrone as an anti-sapstain compound produced by Trichoderma gamsii KUC1747 inhibits the germination of ophiostomatoid fungi. / Hong, Joo Hyun; Lee, Jaejung; Min, Mihee; Ryu, Seung Mok; Lee, Dongho; Kim, Gyu Hyeok; Kim, Jae-Jin.

In: Holzforschung, Vol. 68, No. 7, 01.01.2014, p. 769-774.

Research output: Contribution to journalArticle

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