A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues

Yun Hak Lee, Yonghe Tang, Peter Verwilst, Weiying Lin, Jong Seung Kim

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

A biotin appended formaldehyde sensor was found to specifically visualise both exogenous and endogenous levels of formaldehyde in biotin receptor positive cells over biotin negative cells by means of one- and two-photon excitation. The probe furthermore visualised endogenous levels of formaldehyde in tumour tissue slices up to 70 μm depth.

Original languageEnglish
Pages (from-to)11247-11250
Number of pages4
JournalChemical Communications
Volume52
Issue number75
DOIs
Publication statusPublished - 2016

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Biotin
Formaldehyde
Tissue
Photons
Sensors
Tumors
Cells
Neoplasms

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues. / Lee, Yun Hak; Tang, Yonghe; Verwilst, Peter; Lin, Weiying; Kim, Jong Seung.

In: Chemical Communications, Vol. 52, No. 75, 2016, p. 11247-11250.

Research output: Contribution to journalArticle

Lee, Yun Hak ; Tang, Yonghe ; Verwilst, Peter ; Lin, Weiying ; Kim, Jong Seung. / A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues. In: Chemical Communications. 2016 ; Vol. 52, No. 75. pp. 11247-11250.
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