A brønsted acid catalyst for the enantioselective protonation reaction

Hong Cheon Cheol, Hisashi Yamamoto

Research output: Contribution to journalArticle

188 Citations (Scopus)

Abstract

A highly reactive and robust chiral Brønsted acid catalyst, chiral N-triflyl thiophosphoramide, was developed. The first metal-free Brønsted acid catalyzed enantioselective protonation reaction of silyl enol ethers was demonstrated using this chiral Brønsted acid catalyst. The catalyst loading could be reduced to 0.05 mol % without any deleterious effect on the enantioselectivity.

Original languageEnglish
Pages (from-to)9246-9247
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number29
DOIs
Publication statusPublished - 2008 Jul 23

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'A brønsted acid catalyst for the enantioselective protonation reaction'. Together they form a unique fingerprint.

  • Cite this