A case of auto-immune hepatitis associated with primary Sjogren's syndrome

Yong Dae Kwon, Hong Sik Lee, Chul Hee Park, Yoon Tae Jeen, Hoon-Jai Chun, Sang Woo Lee, Jai Hyun Choi, Chang Duck Kim, Ho Sang Ryu, Jin Hai Hyun

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2 Citations (Scopus)

Abstract

Auto-immune hepatitis is a chronic necroinflammatory liver disorder that is characterized by hypergammaglobulinemia, auto-antibodies in serum, and, on histological examination, the presence of periportal hepatitis. Although it can be associated with a number of other auto-immune diseases, Sjogren's syndrome is rarely associated with auto-immune hepatitis. We herein report an unusual case of auto-immune hepatitis associated with primary Sjogren's syndrome. A 39-year-old woman was admitted to our hospital due to jaundice. Laboratory data showed negative viral hepatitis marker, increased serum IgG level, positive anti- nuclear antibody, and an increased rheumatoid factor titer. The patient had no history of taking medications and alcohol. Based on characteristic clinical features, liver biopsy findings, positive Schirmer's test, and salivary scintigraph, she was diagnosed as having auto-immune hepatitis and Sjogren's syndrome. The patient achieved complete remission with steroid monotherapy.

Original languageEnglish
Pages (from-to)25-30
Number of pages6
JournalTaehan Kan Hakhoe chi = The Korean journal of hepatology
Volume9
Issue number1
Publication statusPublished - 2003 Jan 1

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Sjogren's Syndrome
Hepatitis
Hypergammaglobulinemia
Rheumatoid Factor
Liver
Immune System Diseases
Jaundice
Serum
Anti-Idiotypic Antibodies
Immunoglobulin G
Biomarkers
Steroids
Alcohols
Biopsy
Antibodies

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A case of auto-immune hepatitis associated with primary Sjogren's syndrome. / Kwon, Yong Dae; Lee, Hong Sik; Park, Chul Hee; Jeen, Yoon Tae; Chun, Hoon-Jai; Lee, Sang Woo; Choi, Jai Hyun; Kim, Chang Duck; Ryu, Ho Sang; Hyun, Jin Hai.

In: Taehan Kan Hakhoe chi = The Korean journal of hepatology, Vol. 9, No. 1, 01.01.2003, p. 25-30.

Research output: Contribution to journalArticle

Kwon, Yong Dae ; Lee, Hong Sik ; Park, Chul Hee ; Jeen, Yoon Tae ; Chun, Hoon-Jai ; Lee, Sang Woo ; Choi, Jai Hyun ; Kim, Chang Duck ; Ryu, Ho Sang ; Hyun, Jin Hai. / A case of auto-immune hepatitis associated with primary Sjogren's syndrome. In: Taehan Kan Hakhoe chi = The Korean journal of hepatology. 2003 ; Vol. 9, No. 1. pp. 25-30.
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