A case of CD56+ extranodal NK/T-cell lymphoma, nasal type, presenting as a duodenal ulcer bleeding

Ji Hee Yu, Kee Don Choi, Young Wha Koh, Won Jung Choi, Ho June Song, Gin Hyug Lee, Hwoon Yong Jung, Jin Ho Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Extranodal NK/T-cell lymphoma is a recently recognized distinct entity within the World Health Organization classification of lymphoid tumors. It is relatively prevalent in Asian and South American populations. It most commonly occurs in the nasal or paranasal areas and less frequently in the skin, the soft tissue, and the gastrointestinal tract. Among these, extranodal NK/T-cell lymphoma of the gastrointestinal tract has shown an aggressive clinical course. We report a case of CD56+ extranodal NK/T-cell lymphoma presenting as a duodenal ulcer bleeding. A 62-year-old male patient presented with melena and abdominal pain. Endoscopic examination of the upper gastrointestinal tract showed the duodenal ulcer covered by blood clot. Pathologic examination revealed the diffuse infiltration of atypical lymphocytes with an angiocentric growth pattern, which was positive for CD3, CD56, and granzyme. The patient showed rapid deteriorating clinical course and died on day 14 after admission. Thus, we report this case with the review of literatures.

Original languageEnglish
Pages (from-to)174-179
Number of pages6
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume54
Issue number3
DOIs
Publication statusPublished - 2009 Jan 1
Externally publishedYes

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Extranodal NK-T-Cell Lymphoma
Duodenal Ulcer
Hemorrhage
Gastrointestinal Tract
Melena
Granzymes
Upper Gastrointestinal Tract
Asian Americans
Nose
Abdominal Pain
Thrombosis
Lymphocytes
Skin
Growth
Population
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A case of CD56+ extranodal NK/T-cell lymphoma, nasal type, presenting as a duodenal ulcer bleeding. / Yu, Ji Hee; Choi, Kee Don; Koh, Young Wha; Choi, Won Jung; Song, Ho June; Lee, Gin Hyug; Jung, Hwoon Yong; Kim, Jin Ho.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 54, No. 3, 01.01.2009, p. 174-179.

Research output: Contribution to journalArticle

Yu, Ji Hee ; Choi, Kee Don ; Koh, Young Wha ; Choi, Won Jung ; Song, Ho June ; Lee, Gin Hyug ; Jung, Hwoon Yong ; Kim, Jin Ho. / A case of CD56+ extranodal NK/T-cell lymphoma, nasal type, presenting as a duodenal ulcer bleeding. In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2009 ; Vol. 54, No. 3. pp. 174-179.
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