A case of Dariers disease treated with adapalene

Sang Hwang Eul, Ju Kim Yong, Soo Yu Dong, Jun Song Hae, Hwan Oh Chil

Research output: Contribution to journalReview articlepeer-review


Dariers disease is inherited as an autosomal dominant trait and characterized by follicular pruritic hyperkeratotic papules. The onset is usually in late childhood and the course of the disease is chronic and slowly progressive in most cases. Dariers disease is refractory to treatment with most conventional keratolytics and anti-inflammatory agents. To date, oral and topical retinoid products have been the mainstay therapy for this population, but local as well as systemic side effects often limit their effectiveness. We present a case of localized Dariers disease which responded promptly to the topical application of adapalene 0.1% gel without side effects. A review of treatment for Dariers disease also is presented.

Original languageEnglish
Pages (from-to)425-427
Number of pages3
JournalKorean Journal of Dermatology
Issue number3
Publication statusPublished - 2005 Mar


  • Adapalene
  • Dariers disease

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'A case of Dariers disease treated with adapalene'. Together they form a unique fingerprint.

Cite this