A case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis

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Abstract

Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have been described in the lung parenchyma, airways and pleura, as well as the mediastinum. We report a case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis.

Original languageEnglish
Pages (from-to)179-183
Number of pages5
JournalTuberculosis and Respiratory Diseases
Volume76
Issue number4
DOIs
Publication statusPublished - 2014 Apr

Keywords

  • Immunoglobulin G
  • Pleural effusion
  • Thrombophlebitis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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