A case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis

Jong Hyun Choi, Jae Kyeom Sim, Jee Youn Oh, Eun Joo Lee, Gyu Young Hur, Seung Heon Lee, Sung Yong Lee, Je Hyeong Kim, Sang Yeub Lee, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Kyung Hoon Min

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have been described in the lung parenchyma, airways and pleura, as well as the mediastinum. We report a case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis.

Original languageEnglish
Pages (from-to)179-183
Number of pages5
JournalTuberculosis and Respiratory Diseases
Volume76
Issue number4
DOIs
Publication statusPublished - 2014 Apr

Keywords

  • Immunoglobulin G
  • Pleural effusion
  • Thrombophlebitis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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