A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

Jihyun Yang; Min Young Seo; Ki Tae Kim; Jun Yong Lee; Sun Chul Kim; Myung gyu Kim; Sang Kyung Jo; Won Yong Cho; Hyoung Kyu Kim; Nam Hee Won; Ran Hui Cha; Eunjung Cho Dr

A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

Jihyun Yang, Min Young Seo, Ki Tae Kim, Jun Yong Lee, Sun Chul Kim, Myung gyu Kim, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim, Nam Hee Won, Ran Hui Cha, Eunjung Cho Dr

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

Original language	English
Pages (from-to)	4467-4472
Number of pages	6
Journal	International Journal of Clinical and Experimental Pathology
Volume	7
Issue number	7
Publication status	Published - 2014
Externally published	Yes

Keywords

Glomerulonephritis
HIV-associated nephropathy
Human immunodeficiency virus
Lupus nephritis
Renal biopsy

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level",

abstract = "Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Sch{\"o}lein Purpura (H-S purpura). However, renal biopsy showed {"}lupus-like feature{"} glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.",

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author = "Jihyun Yang and Seo, {Min Young} and Kim, {Ki Tae} and Lee, {Jun Yong} and Kim, {Sun Chul} and Kim, {Myung gyu} and Jo, {Sang Kyung} and Cho, {Won Yong} and Kim, {Hyoung Kyu} and Won, {Nam Hee} and Cha, {Ran Hui} and {Cho Dr}, Eunjung",

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language = "English",

volume = "7",

pages = "4467--4472",

journal = "International Journal of Clinical and Experimental Pathology",

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T1 - A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

AU - Yang, Jihyun

AU - Seo, Min Young

AU - Kim, Ki Tae

AU - Lee, Jun Yong

AU - Kim, Sun Chul

AU - Kim, Myung gyu

AU - Jo, Sang Kyung

AU - Cho, Won Yong

AU - Kim, Hyoung Kyu

AU - Won, Nam Hee

AU - Cha, Ran Hui

AU - Cho Dr, Eunjung

PY - 2014

Y1 - 2014

N2 - Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

AB - Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

KW - Glomerulonephritis

KW - HIV-associated nephropathy

KW - Human immunodeficiency virus

KW - Lupus nephritis

KW - Renal biopsy

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M3 - Article

C2 - 25120835

AN - SCOPUS:84906273353

SN - 1936-2625

VL - 7

SP - 4467

EP - 4472

JO - International Journal of Clinical and Experimental Pathology

JF - International Journal of Clinical and Experimental Pathology

IS - 7

ER -

A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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