A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

Jihyun Yang, Min Young Seo, Ki Tae Kim, Jun Yong Lee, Sun Chul Kim, Myung-Gyu Kim, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim, Nam Hee Won, Ran Hui Cha, Eunjung Cho Dr

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

Original languageEnglish
Pages (from-to)4467-4472
Number of pages6
JournalInternational Journal of Clinical and Experimental Pathology
Volume7
Issue number7
Publication statusPublished - 2014 Jan 1

Keywords

  • Glomerulonephritis
  • HIV-associated nephropathy
  • Human immunodeficiency virus
  • Lupus nephritis
  • Renal biopsy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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