A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

Jihyun Yang, Min Young Seo, Ki Tae Kim, Jun Yong Lee, Sun Chul Kim, Myung-Gyu Kim, Sang Kyung Jo, Won Yong Cho, Hyoung Kyu Kim, Nam Hee Won, Ran Hui Cha, Eunjung Cho Dr

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

Original languageEnglish
Pages (from-to)4467-4472
Number of pages6
JournalInternational Journal of Clinical and Experimental Pathology
Volume7
Issue number7
Publication statusPublished - 2014 Jan 1

Fingerprint

Lupus Nephritis
Purpura
Virus Diseases
Proteinuria
Immunoglobulin A
HIV
Glomerulonephritis
Kidney
Schoenlein-Henoch Purpura
Systemic Lupus Erythematosus
Dialysis
Steroids
Maintenance
Hemorrhage
Biopsy
Therapeutics

Keywords

  • Glomerulonephritis
  • HIV-associated nephropathy
  • Human immunodeficiency virus
  • Lupus nephritis
  • Renal biopsy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level. / Yang, Jihyun; Seo, Min Young; Kim, Ki Tae; Lee, Jun Yong; Kim, Sun Chul; Kim, Myung-Gyu; Jo, Sang Kyung; Cho, Won Yong; Kim, Hyoung Kyu; Won, Nam Hee; Cha, Ran Hui; Cho Dr, Eunjung.

In: International Journal of Clinical and Experimental Pathology, Vol. 7, No. 7, 01.01.2014, p. 4467-4472.

Research output: Contribution to journalArticle

Yang, Jihyun ; Seo, Min Young ; Kim, Ki Tae ; Lee, Jun Yong ; Kim, Sun Chul ; Kim, Myung-Gyu ; Jo, Sang Kyung ; Cho, Won Yong ; Kim, Hyoung Kyu ; Won, Nam Hee ; Cha, Ran Hui ; Cho Dr, Eunjung. / A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level. In: International Journal of Clinical and Experimental Pathology. 2014 ; Vol. 7, No. 7. pp. 4467-4472.
@article{ee6802fa3300442aa1c2136aedbe01b3,
title = "A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level",
abstract = "Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Sch{\"o}lein Purpura (H-S purpura). However, renal biopsy showed {"}lupus-like feature{"} glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.",
keywords = "Glomerulonephritis, HIV-associated nephropathy, Human immunodeficiency virus, Lupus nephritis, Renal biopsy",
author = "Jihyun Yang and Seo, {Min Young} and Kim, {Ki Tae} and Lee, {Jun Yong} and Kim, {Sun Chul} and Myung-Gyu Kim and Jo, {Sang Kyung} and Cho, {Won Yong} and Kim, {Hyoung Kyu} and Won, {Nam Hee} and Cha, {Ran Hui} and {Cho Dr}, Eunjung",
year = "2014",
month = "1",
day = "1",
language = "English",
volume = "7",
pages = "4467--4472",
journal = "International Journal of Clinical and Experimental Pathology",
issn = "1936-2625",
publisher = "e-Century Publishing Corporation",
number = "7",

}

TY - JOUR

T1 - A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

AU - Yang, Jihyun

AU - Seo, Min Young

AU - Kim, Ki Tae

AU - Lee, Jun Yong

AU - Kim, Sun Chul

AU - Kim, Myung-Gyu

AU - Jo, Sang Kyung

AU - Cho, Won Yong

AU - Kim, Hyoung Kyu

AU - Won, Nam Hee

AU - Cha, Ran Hui

AU - Cho Dr, Eunjung

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

AB - Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Schölein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

KW - Glomerulonephritis

KW - HIV-associated nephropathy

KW - Human immunodeficiency virus

KW - Lupus nephritis

KW - Renal biopsy

UR - http://www.scopus.com/inward/record.url?scp=84906273353&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84906273353&partnerID=8YFLogxK

M3 - Article

C2 - 25120835

AN - SCOPUS:84906273353

VL - 7

SP - 4467

EP - 4472

JO - International Journal of Clinical and Experimental Pathology

JF - International Journal of Clinical and Experimental Pathology

SN - 1936-2625

IS - 7

ER -