A case of mottled hypopigmentation after low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet laser therapy

Hwa Jung Ryu, Jiehoon Kim

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)

    Abstract

    Melasma is a very difficult pigmented disease to treat with high recurrence rate. Using low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet (QSNY) lasers repeatedly for the treatment of melasma is now a common practice in East Asia. However, one of the significant side effects is mottled hypopigmentation that appears as scattered white macules in the middle of melasma lesion. The pathophysiology of these hypopigmentation is yet unknown. The biopsy of the hypopigmented lesion showed decreased melanosome with intact melanocytes, and topical tretinoin may be the effective solution for these types of condition.

    Original languageEnglish
    Pages (from-to)290-292
    Number of pages3
    JournalJournal of Cosmetic and Laser Therapy
    Volume15
    Issue number5
    DOIs
    Publication statusPublished - 2013 Oct

    Keywords

    • Lasers and light sources
    • Topical agents

    ASJC Scopus subject areas

    • Surgery
    • Dermatology

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