A case of non-functioning huge adrenocortical carcinoma extending into inferior vena cava and right atrium

Hun Kim Kye, Chun Park Jong, Yup Lim Sang, Suk Sohn Il, Ho Yun Kyung, Hee Cho Sang, Joon Hong Young, Wook Park Hyung, Han Kim Ju, Weon Kim, Keun Ahn Young, Joo Chung Ik, Ho Jeong Myung, Gwan Cho Jeong, Chaee Kang Jung

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Primary adrenocortical carcinoma (ACC) is a rare tumor and its usual sites of metastasis are the lung (71%), lymph node (68%), liver (42%), and bone (26%). However, intracaval invasion extending into the right atrium is very rare and spontaneous regression of tumor burden in adrenal carcinoma is also rare. We report a case of ACC with direct invasion of the inferior vena cava and right atrium. A 34-yr-old male patient presented with progressive dyspnea, weight loss, and poor oral intake over 3 months. Non-functioning ACC with direct invasion of the inferior vena cava and right atrium was confirmed by imaging, pathologic, and hormonal study. Chemo-radiotherapy was attempted. However, tumor burden was not changed, but rather toxic hepatitis and thrombocytopenia were developed. His subjective symptoms and general conditions were improved after 1 month of conservative management and the patient was discharged. During clinical follow-up, this tumor showed spontaneous regression.

Original languageEnglish
Pages (from-to)572-576
Number of pages5
JournalJournal of Korean medical science
Volume21
Issue number3
DOIs
Publication statusPublished - 2006 Jun
Externally publishedYes

Keywords

  • Adrenocortical Carcinoma
  • Neoplasm Metastasis
  • Vena Cava, Inferior

ASJC Scopus subject areas

  • Medicine(all)

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