A case of non-Hodgkin's lymphoma in a patient with neurofibromatosis type 1.

Seok Jin Kim, Jae Hong Seo, Sang Woo Lee, Eunmee Han, Eung Seok Lee, Sang Hoon Cha, Bo Kyoung Seo

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10 Citations (Scopus)


Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called café au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis type 1 was diagnosed as non-Hodgkin's Lymphoma (diffuse large B cell). She had multiple café au lait spots, neurofibromas and right axillary lymph node enlargement. An abdominal CT scan demonstrated a left pelvic mass and para-aortic lymphadenopathy. Because non-Hodgkin's Lymphoma in a neurofibromatosis patient has never been reported in Korea, herein, we describe this case and include a review of the literature.

Original languageEnglish
Pages (from-to)202-205
Number of pages4
JournalThe Korean journal of internal medicine
Issue number3
Publication statusPublished - 2003 Sept
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine


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