A case of non-Hodgkin's lymphoma in a patient with neurofibromatosis type 1.

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Abstract

Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called café au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis type 1 was diagnosed as non-Hodgkin's Lymphoma (diffuse large B cell). She had multiple café au lait spots, neurofibromas and right axillary lymph node enlargement. An abdominal CT scan demonstrated a left pelvic mass and para-aortic lymphadenopathy. Because non-Hodgkin's Lymphoma in a neurofibromatosis patient has never been reported in Korea, herein, we describe this case and include a review of the literature.

Original languageEnglish
Pages (from-to)202-205
Number of pages4
JournalThe Korean journal of internal medicine
Volume18
Issue number3
Publication statusPublished - 2003 Sep 1

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Neurofibromatosis 1
Non-Hodgkin's Lymphoma
Neurofibroma
Nervous System Neoplasms
Skin
Neurofibromatoses
Korea
Lymphoma
B-Lymphocytes
Lymph Nodes
Neoplasms

ASJC Scopus subject areas

  • Internal Medicine

Cite this

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title = "A case of non-Hodgkin's lymphoma in a patient with neurofibromatosis type 1.",
abstract = "Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called caf{\'e} au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis type 1 was diagnosed as non-Hodgkin's Lymphoma (diffuse large B cell). She had multiple caf{\'e} au lait spots, neurofibromas and right axillary lymph node enlargement. An abdominal CT scan demonstrated a left pelvic mass and para-aortic lymphadenopathy. Because non-Hodgkin's Lymphoma in a neurofibromatosis patient has never been reported in Korea, herein, we describe this case and include a review of the literature.",
author = "Kim, {Seok Jin} and Seo, {Jae Hong} and Lee, {Sang Woo} and Eunmee Han and Lee, {Eung Seok} and Cha, {Sang Hoon} and Seo, {Bo Kyoung}",
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T1 - A case of non-Hodgkin's lymphoma in a patient with neurofibromatosis type 1.

AU - Kim, Seok Jin

AU - Seo, Jae Hong

AU - Lee, Sang Woo

AU - Han, Eunmee

AU - Lee, Eung Seok

AU - Cha, Sang Hoon

AU - Seo, Bo Kyoung

PY - 2003/9/1

Y1 - 2003/9/1

N2 - Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called café au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis type 1 was diagnosed as non-Hodgkin's Lymphoma (diffuse large B cell). She had multiple café au lait spots, neurofibromas and right axillary lymph node enlargement. An abdominal CT scan demonstrated a left pelvic mass and para-aortic lymphadenopathy. Because non-Hodgkin's Lymphoma in a neurofibromatosis patient has never been reported in Korea, herein, we describe this case and include a review of the literature.

AB - Neurofibromatosis type 1 is characterized by cutaneous neurofibromas and pigmented lesions of the skin called café au lait spots. Although neurofibromatosis type 1 represents a major risk factor for the development of malignancy, especially of nervous system tumors, malignant lymphoma rarely occurs in a patients with neurofibromatosis type 1. Recently, a 77-year-old woman with neurofibromatosis type 1 was diagnosed as non-Hodgkin's Lymphoma (diffuse large B cell). She had multiple café au lait spots, neurofibromas and right axillary lymph node enlargement. An abdominal CT scan demonstrated a left pelvic mass and para-aortic lymphadenopathy. Because non-Hodgkin's Lymphoma in a neurofibromatosis patient has never been reported in Korea, herein, we describe this case and include a review of the literature.

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