A case of primary pulmonary plasmacytoma presenting as endobronchial mass

Soon Yong Suh, Gang Jee Ko, Chung Ho Kim, Youn Ho Kim, Sung Yong Lee, Sang Yeub Lee, Je Hyeong Kim, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo

Research output: Contribution to journalArticle

Abstract

Extramedullary plasmacytoma(EMP) comprises 5% of all plasma cell neoplasms and commonly occurs in the upper airway or digestive tract. However, it rarely develops in the lungs. We present a case of primary pulmonary plasmacyotma in a 45 year old man, who presented as an endobronchial mass with a pleural effusion, but without evidence of multiple myeloma. The treatment options for EMP include surgery, surgery and radiotherapy, surgery and chemotherapy or chemotherapy alone. Surgery and radiation therapy appeared to be equally effective forms of treatment. The local recurrence rate was reported to be 30%, with 48% progressing to multiple myeloma, and median survival was reported to be 63-101 months. Our patient was initially treated with melphalan and prednisolone. However the disease progressed, and radiotherapy was combined with chemotherapy. In addition, the chemotherapy regimen was also changed to thalidomide and dexamethasone. The patient did not respond to this treatment regimen and finally died.

Original languageEnglish
Pages (from-to)664-669
Number of pages6
JournalTuberculosis and Respiratory Diseases
Volume56
Issue number6
DOIs
Publication statusPublished - 2004 Jun

Keywords

  • Endobronchial mass
  • Extramedullary plasmacytoma
  • Pulmonary plasmacytoma

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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  • Cite this

    Suh, S. Y., Ko, G. J., Kim, C. H., Kim, Y. H., Lee, S. Y., Lee, S. Y., Kim, J. H., Shin, C., Shim, J. J., In, K. H., Kang, K. H., & Yoo, S. H. (2004). A case of primary pulmonary plasmacytoma presenting as endobronchial mass. Tuberculosis and Respiratory Diseases, 56(6), 664-669. https://doi.org/10.4046/trd.2004.56.6.664