A case of primary small cell neuroendocrine carcinoma of the liver

Kyung Jin Kim, Hyung Joon Yim, Min Jeong Kim, Rok Son Choung, Jong Eun Yeon, Hong Sik Lee, Kwan Soo Byun, Sang Woo Lee, Jai Hyun Choi, Ho Sang Ryu, Chang Hong Lee, Jin Hai Hyun, Eung Suk Lee, Young Sik Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Small cell neuroendocrine carcinoma is a type of undifferentiated, malignant neuroendocrine tumor. Most of neuroendocrine tumors exhibit well-differentiated features and are classified as carcinoid tumors. However, carcinomas of the liver with anaplastic characters, which are classified as small-cell carcinomas are extremely rare and only few cases have been reported in the literature. We report an unusual case of primary small cell neuroendocrine carcinoma of the liver in a 67-year-old man. The patient was found to have a palpable mass on right upper quadrant of abdomen on physical examination. The diagnosis was made by immunohistochemical stains of biopsied specimen from the liver. Other possible primary site was excluded by radiologic and endoscopic evaluations. The tumor was composed of small monotonous and hyperchromatic poorly differentiated cells with higher nuclear to cytoplasmic ratio, and were positive for neuroendocrine tissue markers such as synaptophysin, c-kit, and CD56.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume48
Issue number1
Publication statusPublished - 2006 Jul 1

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Neuroendocrine Carcinoma
Small Cell Carcinoma
Neuroendocrine Tumors
Liver
Synaptophysin
Carcinoid Tumor
Abdomen
Physical Examination
Coloring Agents
Carcinoma
Neoplasms

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A case of primary small cell neuroendocrine carcinoma of the liver. / Kim, Kyung Jin; Yim, Hyung Joon; Kim, Min Jeong; Choung, Rok Son; Yeon, Jong Eun; Lee, Hong Sik; Byun, Kwan Soo; Lee, Sang Woo; Choi, Jai Hyun; Ryu, Ho Sang; Lee, Chang Hong; Hyun, Jin Hai; Lee, Eung Suk; Kim, Young Sik.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 48, No. 1, 01.07.2006, p. 37-41.

Research output: Contribution to journalArticle

Kim, Kyung Jin ; Yim, Hyung Joon ; Kim, Min Jeong ; Choung, Rok Son ; Yeon, Jong Eun ; Lee, Hong Sik ; Byun, Kwan Soo ; Lee, Sang Woo ; Choi, Jai Hyun ; Ryu, Ho Sang ; Lee, Chang Hong ; Hyun, Jin Hai ; Lee, Eung Suk ; Kim, Young Sik. / A case of primary small cell neuroendocrine carcinoma of the liver. In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2006 ; Vol. 48, No. 1. pp. 37-41.
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