A case of refractory vitiligo that was treated with a combination of non-ablative 1550-nm erbium

Glass fractional laser, narrow-band UVB, and a topical agent

Jae Beom Park, Ji Hyun Park, Seung Hyun Chun, Hee Won Jang, Hwa Jung Ryu, Il-Hwan Kim

Research output: Contribution to journalArticle

Abstract

TThere are many therapeutic methods for treating vitiligo, including narrow-band UVB, topical corticosteroids, calcineurin inhibitors, excimer laser, and surgical methods, such as autologous epidermal grafting and dermabrasion. However, although various treatments have been tried, there is still no reliable treatment. Recently, there were several reports about the use of fractional laser combined with narrow-band (NB) UVB to treat vitiligo. A 33-year-old male patient presented with hypopigmented patch on lower right abdominal area. After being diagnosed with vitiligo, the patient underwent NB-UVB treatment and application of a topical agent for two years but failed to show response. To evaluate the efficacy of non-ablative fractional laser, a 1550-nm erbium:glass (EnGlass) fractional laser was applied to whole area of the lesion. The area showed erythema and brown microscopic epidermal necrotic debris. Five days after the laser procedure, NB-UVB treatment with application of a topical agent was initiated once or twice a week, followed by pigmentation of the treated area. The fractional laser was reapplied three months later, and the patient is currently under observation and is still being treated with NB-UVB. We observed successful treatment of refractory vitiligo with the combination of non-ablative 1550-nm EnGlass fractional laser, NB-UVB, and a topical agent. We consider non-ablative EnGlass fractional laser as a favorable choice of treatment for refractory vitiligo.

Original languageEnglish
Pages (from-to)280-283
Number of pages4
JournalKorean Journal of Dermatology
Volume54
Issue number4
Publication statusPublished - 2016 May 1

Fingerprint

Erbium
Vitiligo
Glass
Lasers
Therapeutics
Dermabrasion
Excimer Lasers
Pigmentation
Erythema
Adrenal Cortex Hormones
Observation

Keywords

  • Non-ablative 1550-nm EnGlass fractional laser
  • Refractory vitiligo

ASJC Scopus subject areas

  • Dermatology

Cite this

A case of refractory vitiligo that was treated with a combination of non-ablative 1550-nm erbium : Glass fractional laser, narrow-band UVB, and a topical agent. / Park, Jae Beom; Park, Ji Hyun; Chun, Seung Hyun; Jang, Hee Won; Ryu, Hwa Jung; Kim, Il-Hwan.

In: Korean Journal of Dermatology, Vol. 54, No. 4, 01.05.2016, p. 280-283.

Research output: Contribution to journalArticle

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abstract = "TThere are many therapeutic methods for treating vitiligo, including narrow-band UVB, topical corticosteroids, calcineurin inhibitors, excimer laser, and surgical methods, such as autologous epidermal grafting and dermabrasion. However, although various treatments have been tried, there is still no reliable treatment. Recently, there were several reports about the use of fractional laser combined with narrow-band (NB) UVB to treat vitiligo. A 33-year-old male patient presented with hypopigmented patch on lower right abdominal area. After being diagnosed with vitiligo, the patient underwent NB-UVB treatment and application of a topical agent for two years but failed to show response. To evaluate the efficacy of non-ablative fractional laser, a 1550-nm erbium:glass (EnGlass) fractional laser was applied to whole area of the lesion. The area showed erythema and brown microscopic epidermal necrotic debris. Five days after the laser procedure, NB-UVB treatment with application of a topical agent was initiated once or twice a week, followed by pigmentation of the treated area. The fractional laser was reapplied three months later, and the patient is currently under observation and is still being treated with NB-UVB. We observed successful treatment of refractory vitiligo with the combination of non-ablative 1550-nm EnGlass fractional laser, NB-UVB, and a topical agent. We consider non-ablative EnGlass fractional laser as a favorable choice of treatment for refractory vitiligo.",
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