A case of relapsing polychondritis involved tracheobronchial tree

S. Y. Lee, Youn Cho Jae Youn Cho, La Lee So La Lee, Hwa Lee Sang Hwa Lee, Kyung Suh Jung Kyung Suh, Jeong Shim Jae Jeong Shim, Gyu Song Gwan Gyu Song, Ho In Kwang Ho In, Ho Kang Kyung Ho Kang, Hwa Yoo Se Hwa Yoo

Research output: Contribution to journalArticle

Abstract

Relapsing polychondritis is a systemic disorder characterized by recurrent inflammation and degeneration of cartilaginous tissue throughout the body. The association with HLA-DR4 and the occurrence of antibodies to type II collagen and other autoantibodies suggest that an immunologic mechanism is involved in its pathogenesis. The eyes, ears, nose, larynx, trachea and articular areas are commonly involved. Airway narrowing or collapse from respiratory tract involvement occurs in up to 50% of patients with relapsing polychondritis. Treatment consists of administration of corticosteroids and other anti-inflammatory and immunosuppressive drugs. We experienced a case of relapsing polychondritis involving the tracheobronchial tree, nose and ears in a 49-year-old woman. The patient was clinically and histologically diagnosed as relapsing polychondritis according to McAdam's and Damiani's criteria. We report this case with a review of the literature.

Original languageEnglish
Pages (from-to)922-929
Number of pages8
JournalTuberculosis and Respiratory Diseases
Volume44
Issue number4
DOIs
Publication statusPublished - 1997

Keywords

  • Relapsing polychondritis
  • Tracheobronchus

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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