A case of spitzoid melanoma with lymph node metastasis in a child

Jong Yeob Kim, Jae Eun Choi, Hyo Hyun Ahn, Young Chul Kye, Soo-Hong Seo

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The distinction of a spitz nevus from a melanoma can be difficult and in some cases, impossible. A misdiagnosed spitz nevus can metastasize and lead to fatal outcomes, especially in children. A 5-yr-old girl presented with a 1-yr history of a solitary pinkish nodule on her left hand. On physical examination, she had a palpable left axillary lymph node. We performed biopsy and checked 3 sentinel lymph nodes (SLN) on her axillary area. The biopsy specimen showed multiple variably sized and shaped nests with large spindle or polygonal cells and SLN biopsy showed 3 of 3 lymph nodes that were metastasized. Under the diagnosis of spitzoid melanoma, she was treated with excision biopsy and complete left axillary lymph nodes were dissected. She received interferon-α2b subcutaneously at a dose of 8 MIU per day, 3 times weekly for 12 months, and shows no recurrence.

Original languageEnglish
Pages (from-to)454-457
Number of pages4
JournalJournal of Korean Medical Science
Volume27
Issue number4
DOIs
Publication statusPublished - 2012 Apr 1

Fingerprint

Epithelioid and Spindle Cell Nevus
Melanoma
Lymph Nodes
Neoplasm Metastasis
Biopsy
Nevi and Melanomas
Sentinel Lymph Node Biopsy
Fatal Outcome
Diagnostic Errors
Interferons
Physical Examination
Hand
Recurrence

Keywords

  • Child
  • Lymph node metastasis
  • Spitz nevus
  • Spitzoid melanoma

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A case of spitzoid melanoma with lymph node metastasis in a child. / Kim, Jong Yeob; Choi, Jae Eun; Ahn, Hyo Hyun; Kye, Young Chul; Seo, Soo-Hong.

In: Journal of Korean Medical Science, Vol. 27, No. 4, 01.04.2012, p. 454-457.

Research output: Contribution to journalArticle

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AB - The distinction of a spitz nevus from a melanoma can be difficult and in some cases, impossible. A misdiagnosed spitz nevus can metastasize and lead to fatal outcomes, especially in children. A 5-yr-old girl presented with a 1-yr history of a solitary pinkish nodule on her left hand. On physical examination, she had a palpable left axillary lymph node. We performed biopsy and checked 3 sentinel lymph nodes (SLN) on her axillary area. The biopsy specimen showed multiple variably sized and shaped nests with large spindle or polygonal cells and SLN biopsy showed 3 of 3 lymph nodes that were metastasized. Under the diagnosis of spitzoid melanoma, she was treated with excision biopsy and complete left axillary lymph nodes were dissected. She received interferon-α2b subcutaneously at a dose of 8 MIU per day, 3 times weekly for 12 months, and shows no recurrence.

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