A case of verrucous carcinoma treated by 5% imiquimod cream

Ji Woong, Jae Eun Choi, Hyo Hyun Ahn, Young Chul Kye, Soo Nam Kim

Research output: Contribution to journalArticle

Abstract

Verrucous carcinoma is a slow-growing, well-differentiated, low grade squamous cell carcinoma with little tendency to metastasize. The best treatment for verrucous carcinoma is excision, and Mohs microsurgery may also be a helpful technique. But some people can not undergo surgical excision because of poor general condition of the site and the size of the tumor. Herein, we report a case of verrucous carcinoma treated by 5% imiquimod cream. A 71-year-old male patient presented with a large hyperkeratotic verrucous plaque on the Rt. buttock. Diagnosis of verrucous carcinoma was based on typical clinical and histologic features. Surgical excision could not be performed due to me size of the tumor. Treatment with 5% imiquimod cream, a topical immune response modifier, applied every other day for 16 weeks, led to tumor regression. Four weeks after tibe end of treatment, the lesion was evaluated by punch biopsy. The histology just showed scar tissue change. This case demonstrates that the imiquimod cream might be an alternative treatment option for verrucous carcinoma.

Original languageEnglish
Pages (from-to)851-854
Number of pages4
JournalKorean Journal of Dermatology
Volume46
Issue number6
Publication statusPublished - 2008 Jun 1

Fingerprint

imiquimod
Verrucous Carcinoma
Neoplasms
Buttocks
Microsurgery
Therapeutics
Cicatrix
Squamous Cell Carcinoma
Histology
Biopsy

Keywords

  • Imiquimod
  • Verrucous carcinoma

ASJC Scopus subject areas

  • Dermatology

Cite this

A case of verrucous carcinoma treated by 5% imiquimod cream. / Woong, Ji; Choi, Jae Eun; Ahn, Hyo Hyun; Kye, Young Chul; Kim, Soo Nam.

In: Korean Journal of Dermatology, Vol. 46, No. 6, 01.06.2008, p. 851-854.

Research output: Contribution to journalArticle

Woong, Ji ; Choi, Jae Eun ; Ahn, Hyo Hyun ; Kye, Young Chul ; Kim, Soo Nam. / A case of verrucous carcinoma treated by 5% imiquimod cream. In: Korean Journal of Dermatology. 2008 ; Vol. 46, No. 6. pp. 851-854.
@article{3cbb27f24e464e15beda97b05df3f775,
title = "A case of verrucous carcinoma treated by 5{\%} imiquimod cream",
abstract = "Verrucous carcinoma is a slow-growing, well-differentiated, low grade squamous cell carcinoma with little tendency to metastasize. The best treatment for verrucous carcinoma is excision, and Mohs microsurgery may also be a helpful technique. But some people can not undergo surgical excision because of poor general condition of the site and the size of the tumor. Herein, we report a case of verrucous carcinoma treated by 5{\%} imiquimod cream. A 71-year-old male patient presented with a large hyperkeratotic verrucous plaque on the Rt. buttock. Diagnosis of verrucous carcinoma was based on typical clinical and histologic features. Surgical excision could not be performed due to me size of the tumor. Treatment with 5{\%} imiquimod cream, a topical immune response modifier, applied every other day for 16 weeks, led to tumor regression. Four weeks after tibe end of treatment, the lesion was evaluated by punch biopsy. The histology just showed scar tissue change. This case demonstrates that the imiquimod cream might be an alternative treatment option for verrucous carcinoma.",
keywords = "Imiquimod, Verrucous carcinoma",
author = "Ji Woong and Choi, {Jae Eun} and Ahn, {Hyo Hyun} and Kye, {Young Chul} and Kim, {Soo Nam}",
year = "2008",
month = "6",
day = "1",
language = "English",
volume = "46",
pages = "851--854",
journal = "Korean Journal of Dermatology",
issn = "0494-4739",
publisher = "Korean Dermatological Association",
number = "6",

}

TY - JOUR

T1 - A case of verrucous carcinoma treated by 5% imiquimod cream

AU - Woong, Ji

AU - Choi, Jae Eun

AU - Ahn, Hyo Hyun

AU - Kye, Young Chul

AU - Kim, Soo Nam

PY - 2008/6/1

Y1 - 2008/6/1

N2 - Verrucous carcinoma is a slow-growing, well-differentiated, low grade squamous cell carcinoma with little tendency to metastasize. The best treatment for verrucous carcinoma is excision, and Mohs microsurgery may also be a helpful technique. But some people can not undergo surgical excision because of poor general condition of the site and the size of the tumor. Herein, we report a case of verrucous carcinoma treated by 5% imiquimod cream. A 71-year-old male patient presented with a large hyperkeratotic verrucous plaque on the Rt. buttock. Diagnosis of verrucous carcinoma was based on typical clinical and histologic features. Surgical excision could not be performed due to me size of the tumor. Treatment with 5% imiquimod cream, a topical immune response modifier, applied every other day for 16 weeks, led to tumor regression. Four weeks after tibe end of treatment, the lesion was evaluated by punch biopsy. The histology just showed scar tissue change. This case demonstrates that the imiquimod cream might be an alternative treatment option for verrucous carcinoma.

AB - Verrucous carcinoma is a slow-growing, well-differentiated, low grade squamous cell carcinoma with little tendency to metastasize. The best treatment for verrucous carcinoma is excision, and Mohs microsurgery may also be a helpful technique. But some people can not undergo surgical excision because of poor general condition of the site and the size of the tumor. Herein, we report a case of verrucous carcinoma treated by 5% imiquimod cream. A 71-year-old male patient presented with a large hyperkeratotic verrucous plaque on the Rt. buttock. Diagnosis of verrucous carcinoma was based on typical clinical and histologic features. Surgical excision could not be performed due to me size of the tumor. Treatment with 5% imiquimod cream, a topical immune response modifier, applied every other day for 16 weeks, led to tumor regression. Four weeks after tibe end of treatment, the lesion was evaluated by punch biopsy. The histology just showed scar tissue change. This case demonstrates that the imiquimod cream might be an alternative treatment option for verrucous carcinoma.

KW - Imiquimod

KW - Verrucous carcinoma

UR - http://www.scopus.com/inward/record.url?scp=51349085971&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51349085971&partnerID=8YFLogxK

M3 - Article

VL - 46

SP - 851

EP - 854

JO - Korean Journal of Dermatology

JF - Korean Journal of Dermatology

SN - 0494-4739

IS - 6

ER -