A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253

Won Seok Jung, Young Ji Yoo, Je Won Park, Sung Ryeol Park, Ah Reum Han, Yeon Hee Ban, Eun Ji Kim, Eunji Kim, Yeo Joon Yoon

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