A comparison of clinical characteristics of older adults treated with antidepressants in general and psychiatric hospitals in Asia

Yuan Yuan Wang, Yu Tao Xiang, Gabor S. Ungvari, Chee H. Ng, Helen F.K. Chiu, Larina C.L. Yim, Tian Mei Si, Kok Yoon Chee, Ajit Avasthi, Sandeep Grover, Mian Yoon Chong, Kang Sim, Shigenobu Kanba, Yan Ling He, Min-Soo Lee, Shu Yu Yang, Pichet Udomratn, Roy A. Kallivayalil, Andi J. Tanra, Margarita M. MaramisWinston W. Shen, Norman Sartorius, Rathi Mahendran, Jia Ying Teng, Chay Hoon Tan, Naotaka Shinfuku

Research output: Contribution to journalArticle

2 Citations (Scopus)


Aim: This study compared the demographics, clinical characteristics, and antidepressant prescription patterns between Asian patients aged 50 years and older attending psychiatric hospitals and those attending general hospitals. Methods: In total, 955 patients (604 in general hospitals, 351 in psychiatric hospitals) aged 50 years or older treated with antidepressants in 10 Asian countries and territories were examined. Patients’ demographics, clinical features, and prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. Results: Binary logistic regression revealed that high income and diagnosis of schizophrenia were independently associated with psychiatric hospital treatment, whereas outpatient care, diagnosis of anxiety disorders, and multiple major medical conditions were independently associated with general hospital treatment. In addition, tetracyclic and noradrenergic and specific serotonergic antidepressants were more likely to be prescribed in general hospitals. Conclusion: Older adults treated with antidepressants showed different demographic and clinical features between general hospitals and psychiatric hospitals in Asia.

Original languageEnglish
Pages (from-to)348-355
Number of pages8
Issue number6
Publication statusPublished - 2017 Nov 1



  • antidepressants
  • Asia
  • prescription patterns

ASJC Scopus subject areas

  • Gerontology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this

Wang, Y. Y., Xiang, Y. T., Ungvari, G. S., Ng, C. H., Chiu, H. F. K., Yim, L. C. L., Si, T. M., Chee, K. Y., Avasthi, A., Grover, S., Chong, M. Y., Sim, K., Kanba, S., He, Y. L., Lee, M-S., Yang, S. Y., Udomratn, P., Kallivayalil, R. A., Tanra, A. J., ... Shinfuku, N. (2017). A comparison of clinical characteristics of older adults treated with antidepressants in general and psychiatric hospitals in Asia. Psychogeriatrics, 17(6), 348-355. https://doi.org/10.1111/psyg.12243