A comparison of digital tomosynthesis and chest radiography in evaluating airway lesions using computed tomography as a reference

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Abstract

Objectives: To compare the diagnostic performance of digital tomosynthesis (DTS) and chest radiography for detecting airway abnormalities, using computed tomography (CT) as a reference. Materials and methods: We evaluated 161 data sets from 149 patients (91 with and 70 without airway abnormalities) who had undergone radiography, DTS, and CT to detect airway problems. Radiographs and DTS were evaluated to localize and score the severity of the airway abnormalities, and to score the image quality using CT as a reference. Receiver operating characteristics (ROC), McNemar’s test, weighted kappa, and the paired t-test were used for statistical analysis. Results: The sensitivity of DTS was higher (reader 1, 93.51 %; reader 2, 94.29 %) than chest radiography (68.83 %; 71.43 %) in detecting airway lesions. The diagnostic accuracy of DTS (90.91 %; 94.70 %) was also significantly better than that of radiography (78.03 %; 82.58 %, all p < 0.05). DTS image quality was significantly better than chest radiography (1.83, 2.74; p < 0.05) in the results of both readers. The inter-observer agreement with respect to DTS findings was moderate and superior when compared to radiography findings. Conclusions: DTS is a more accurate and sensitive modality than radiography for detecting airway lesions that are easily obscured by soft tissue structures in the mediastinum. Key Points: • Digital tomosynthesis offers new diagnostic options for airway lesions. • Digital tomosynthesis is more sensitive and accurate than radiography for airway lesions. • Digital tomosynthesis shows better image quality than radiography. • Assessment of lesion severity, via tomosynthesis is comparable to computed tomography.

Original languageEnglish
Pages (from-to)3147-3154
Number of pages8
JournalEuropean Radiology
Volume26
Issue number9
DOIs
Publication statusPublished - 2016 Sep 1

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Radiography
Thorax
Tomography
Radiographic Image Enhancement
Mediastinum
ROC Curve

Keywords

  • Airway disease
  • Chest radiography
  • Computed tomography
  • Digital tomosynthesis
  • Radiation dose

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

@article{29940e49d6624b219ffdfece41d8ec62,
title = "A comparison of digital tomosynthesis and chest radiography in evaluating airway lesions using computed tomography as a reference",
abstract = "Objectives: To compare the diagnostic performance of digital tomosynthesis (DTS) and chest radiography for detecting airway abnormalities, using computed tomography (CT) as a reference. Materials and methods: We evaluated 161 data sets from 149 patients (91 with and 70 without airway abnormalities) who had undergone radiography, DTS, and CT to detect airway problems. Radiographs and DTS were evaluated to localize and score the severity of the airway abnormalities, and to score the image quality using CT as a reference. Receiver operating characteristics (ROC), McNemar’s test, weighted kappa, and the paired t-test were used for statistical analysis. Results: The sensitivity of DTS was higher (reader 1, 93.51 {\%}; reader 2, 94.29 {\%}) than chest radiography (68.83 {\%}; 71.43 {\%}) in detecting airway lesions. The diagnostic accuracy of DTS (90.91 {\%}; 94.70 {\%}) was also significantly better than that of radiography (78.03 {\%}; 82.58 {\%}, all p < 0.05). DTS image quality was significantly better than chest radiography (1.83, 2.74; p < 0.05) in the results of both readers. The inter-observer agreement with respect to DTS findings was moderate and superior when compared to radiography findings. Conclusions: DTS is a more accurate and sensitive modality than radiography for detecting airway lesions that are easily obscured by soft tissue structures in the mediastinum. Key Points: • Digital tomosynthesis offers new diagnostic options for airway lesions. • Digital tomosynthesis is more sensitive and accurate than radiography for airway lesions. • Digital tomosynthesis shows better image quality than radiography. • Assessment of lesion severity, via tomosynthesis is comparable to computed tomography.",
keywords = "Airway disease, Chest radiography, Computed tomography, Digital tomosynthesis, Radiation dose",
author = "Choo, {Ji Yung} and Lee, {Ki Yeol} and Ami Yu and Kim, {Je Hyeong} and Lee, {Seung Heon} and Jung-Woo Choi and Eun-Young Kang and Oh, {Yu Whan}",
year = "2016",
month = "9",
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doi = "10.1007/s00330-015-4127-z",
language = "English",
volume = "26",
pages = "3147--3154",
journal = "European Radiology",
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T1 - A comparison of digital tomosynthesis and chest radiography in evaluating airway lesions using computed tomography as a reference

AU - Choo, Ji Yung

AU - Lee, Ki Yeol

AU - Yu, Ami

AU - Kim, Je Hyeong

AU - Lee, Seung Heon

AU - Choi, Jung-Woo

AU - Kang, Eun-Young

AU - Oh, Yu Whan

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Objectives: To compare the diagnostic performance of digital tomosynthesis (DTS) and chest radiography for detecting airway abnormalities, using computed tomography (CT) as a reference. Materials and methods: We evaluated 161 data sets from 149 patients (91 with and 70 without airway abnormalities) who had undergone radiography, DTS, and CT to detect airway problems. Radiographs and DTS were evaluated to localize and score the severity of the airway abnormalities, and to score the image quality using CT as a reference. Receiver operating characteristics (ROC), McNemar’s test, weighted kappa, and the paired t-test were used for statistical analysis. Results: The sensitivity of DTS was higher (reader 1, 93.51 %; reader 2, 94.29 %) than chest radiography (68.83 %; 71.43 %) in detecting airway lesions. The diagnostic accuracy of DTS (90.91 %; 94.70 %) was also significantly better than that of radiography (78.03 %; 82.58 %, all p < 0.05). DTS image quality was significantly better than chest radiography (1.83, 2.74; p < 0.05) in the results of both readers. The inter-observer agreement with respect to DTS findings was moderate and superior when compared to radiography findings. Conclusions: DTS is a more accurate and sensitive modality than radiography for detecting airway lesions that are easily obscured by soft tissue structures in the mediastinum. Key Points: • Digital tomosynthesis offers new diagnostic options for airway lesions. • Digital tomosynthesis is more sensitive and accurate than radiography for airway lesions. • Digital tomosynthesis shows better image quality than radiography. • Assessment of lesion severity, via tomosynthesis is comparable to computed tomography.

AB - Objectives: To compare the diagnostic performance of digital tomosynthesis (DTS) and chest radiography for detecting airway abnormalities, using computed tomography (CT) as a reference. Materials and methods: We evaluated 161 data sets from 149 patients (91 with and 70 without airway abnormalities) who had undergone radiography, DTS, and CT to detect airway problems. Radiographs and DTS were evaluated to localize and score the severity of the airway abnormalities, and to score the image quality using CT as a reference. Receiver operating characteristics (ROC), McNemar’s test, weighted kappa, and the paired t-test were used for statistical analysis. Results: The sensitivity of DTS was higher (reader 1, 93.51 %; reader 2, 94.29 %) than chest radiography (68.83 %; 71.43 %) in detecting airway lesions. The diagnostic accuracy of DTS (90.91 %; 94.70 %) was also significantly better than that of radiography (78.03 %; 82.58 %, all p < 0.05). DTS image quality was significantly better than chest radiography (1.83, 2.74; p < 0.05) in the results of both readers. The inter-observer agreement with respect to DTS findings was moderate and superior when compared to radiography findings. Conclusions: DTS is a more accurate and sensitive modality than radiography for detecting airway lesions that are easily obscured by soft tissue structures in the mediastinum. Key Points: • Digital tomosynthesis offers new diagnostic options for airway lesions. • Digital tomosynthesis is more sensitive and accurate than radiography for airway lesions. • Digital tomosynthesis shows better image quality than radiography. • Assessment of lesion severity, via tomosynthesis is comparable to computed tomography.

KW - Airway disease

KW - Chest radiography

KW - Computed tomography

KW - Digital tomosynthesis

KW - Radiation dose

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