A comprehensive review of the treatment of atopic eczema

Ji Hyun Lee, Sang Wook Son, Sang Hyun Cho

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

Atopic eczema (AE) is a chronic, inflammatory skin disorder which usually develops in early childhood. In spite of intensive investigations, the causes of AE remain unclear, but are likely to be multifactorial in nature. Environmental factors or genetic-environmental interactions seem to play a key role in disease progression. Among various measures of AE managment, cutaneous hydration, which improves barrier function and relieve itchiness, may be helpful to reduce the need for topical steroid use and therefore should be used as a basic treatment. Avoiding aggravating factors is also a basic treatment of AE. Standard medical treatment with a pharmacologic approach may be necessary if basic treatment fails to control symptoms satisfactorily. Recently, more attention is given to a proactive therapeutic by regular intermittent application of low potency steroids or topical calcineurin inhibitors to prevent new flares. Furthermore, various targeted biologics are being introduced for AE control and are proposed as promising therapies. This paper provides a summary of the recent literature on the manangement of AE and a treatment guideline.

Original languageEnglish
Pages (from-to)181-190
Number of pages10
JournalAllergy, Asthma and Immunology Research
Volume8
Issue number3
DOIs
Publication statusPublished - 2016

Fingerprint

Atopic Dermatitis
Steroids
Skin
Biological Products
Disease Progression
Guidelines
Therapeutics

Keywords

  • Atopic dermatitis
  • Atopic eczema
  • Eczema
  • Epidemiology
  • Prevention
  • Ttreatment

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine

Cite this

A comprehensive review of the treatment of atopic eczema. / Lee, Ji Hyun; Son, Sang Wook; Cho, Sang Hyun.

In: Allergy, Asthma and Immunology Research, Vol. 8, No. 3, 2016, p. 181-190.

Research output: Contribution to journalReview article

Lee, Ji Hyun ; Son, Sang Wook ; Cho, Sang Hyun. / A comprehensive review of the treatment of atopic eczema. In: Allergy, Asthma and Immunology Research. 2016 ; Vol. 8, No. 3. pp. 181-190.
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