TY - GEN
T1 - A computational method for longitudinal mapping of orientation-specific expansion of cortical surface area in infants
AU - Xia, Jing
AU - Zhang, Caiming
AU - Wang, Fan
AU - Meng, Yu
AU - Wu, Zhengwang
AU - Wang, Li
AU - Lin, Weili
AU - Shen, Dinggang
AU - Li, Gang
N1 - Publisher Copyright:
© 2018 IEEE.
PY - 2018/5/23
Y1 - 2018/5/23
N2 - The dynamic expansion of the human cortical surface during infancy is largely driven by the increase of surface area in two orthogonal directions: 1) the expansion parallel to the folding orientation (i.e., increasing the lengths of folds) and 2) the expansion perpendicular to the folding orientation (i.e., increasing the depths of folds). The knowledge on this would help us better understand the cortical growth mechanisms and provide important insights into neurodevelopmental disorders, but still remains scarce, due to the lack of dedicated computational methods. To address this issue, we propose a novel method for longitudinal mapping of orientation-specific expansion of cortical surface area in these two orthogonal directions during early infancy. We apply our method to30 healthy infants, and for the first time reveal the orientation-specific longitudinal cortical surface expansion maps during the first postnatal year.
AB - The dynamic expansion of the human cortical surface during infancy is largely driven by the increase of surface area in two orthogonal directions: 1) the expansion parallel to the folding orientation (i.e., increasing the lengths of folds) and 2) the expansion perpendicular to the folding orientation (i.e., increasing the depths of folds). The knowledge on this would help us better understand the cortical growth mechanisms and provide important insights into neurodevelopmental disorders, but still remains scarce, due to the lack of dedicated computational methods. To address this issue, we propose a novel method for longitudinal mapping of orientation-specific expansion of cortical surface area in these two orthogonal directions during early infancy. We apply our method to30 healthy infants, and for the first time reveal the orientation-specific longitudinal cortical surface expansion maps during the first postnatal year.
KW - Cortical folding
KW - Graph cuts
KW - Longitudinal development
KW - Orientation fields
KW - Surface expansion
UR - http://www.scopus.com/inward/record.url?scp=85048127329&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2018.8363666
DO - 10.1109/ISBI.2018.8363666
M3 - Conference contribution
AN - SCOPUS:85048127329
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 683
EP - 686
BT - 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018
PB - IEEE Computer Society
T2 - 15th IEEE International Symposium on Biomedical Imaging, ISBI 2018
Y2 - 4 April 2018 through 7 April 2018
ER -
