Abstract
The dynamic expansion of the human cortical surface during infancy is largely driven by the increase of surface area in two orthogonal directions: 1) the expansion parallel to the folding orientation (i.e., increasing the lengths of folds) and 2) the expansion perpendicular to the folding orientation (i.e., increasing the depths of folds). The knowledge on this would help us better understand the cortical growth mechanisms and provide important insights into neurodevelopmental disorders, but still remains scarce, due to the lack of dedicated computational methods. To address this issue, we propose a novel method for longitudinal mapping of orientation-specific expansion of cortical surface area in these two orthogonal directions during early infancy. We apply our method to30 healthy infants, and for the first time reveal the orientation-specific longitudinal cortical surface expansion maps during the first postnatal year.
| Original language | English |
|---|---|
| Title of host publication | 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018 |
| Publisher | IEEE Computer Society |
| Pages | 683-686 |
| Number of pages | 4 |
| Volume | 2018-April |
| ISBN (Electronic) | 9781538636367 |
| DOIs | |
| Publication status | Published - 2018 May 23 |
| Externally published | Yes |
| Event | 15th IEEE International Symposium on Biomedical Imaging, ISBI 2018 - Washington, United States Duration: 2018 Apr 4 → 2018 Apr 7 |
Other
| Other | 15th IEEE International Symposium on Biomedical Imaging, ISBI 2018 |
|---|---|
| Country | United States |
| City | Washington |
| Period | 18/4/4 → 18/4/7 |
Fingerprint
Keywords
- Cortical folding
- Graph cuts
- Longitudinal development
- Orientation fields
- Surface expansion
ASJC Scopus subject areas
- Biomedical Engineering
- Radiology Nuclear Medicine and imaging
Cite this
A computational method for longitudinal mapping of orientation-specific expansion of cortical surface area in infants. / Xia, Jing; Zhang, Caiming; Wang, Fan; Meng, Yu; Wu, Zhengwang; Wang, Li; Lin, Weili; Shen, Dinggang; Li, Gang.
2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. Vol. 2018-April IEEE Computer Society, 2018. p. 683-686.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - A computational method for longitudinal mapping of orientation-specific expansion of cortical surface area in infants
AU - Xia, Jing
AU - Zhang, Caiming
AU - Wang, Fan
AU - Meng, Yu
AU - Wu, Zhengwang
AU - Wang, Li
AU - Lin, Weili
AU - Shen, Dinggang
AU - Li, Gang
PY - 2018/5/23
Y1 - 2018/5/23
N2 - The dynamic expansion of the human cortical surface during infancy is largely driven by the increase of surface area in two orthogonal directions: 1) the expansion parallel to the folding orientation (i.e., increasing the lengths of folds) and 2) the expansion perpendicular to the folding orientation (i.e., increasing the depths of folds). The knowledge on this would help us better understand the cortical growth mechanisms and provide important insights into neurodevelopmental disorders, but still remains scarce, due to the lack of dedicated computational methods. To address this issue, we propose a novel method for longitudinal mapping of orientation-specific expansion of cortical surface area in these two orthogonal directions during early infancy. We apply our method to30 healthy infants, and for the first time reveal the orientation-specific longitudinal cortical surface expansion maps during the first postnatal year.
AB - The dynamic expansion of the human cortical surface during infancy is largely driven by the increase of surface area in two orthogonal directions: 1) the expansion parallel to the folding orientation (i.e., increasing the lengths of folds) and 2) the expansion perpendicular to the folding orientation (i.e., increasing the depths of folds). The knowledge on this would help us better understand the cortical growth mechanisms and provide important insights into neurodevelopmental disorders, but still remains scarce, due to the lack of dedicated computational methods. To address this issue, we propose a novel method for longitudinal mapping of orientation-specific expansion of cortical surface area in these two orthogonal directions during early infancy. We apply our method to30 healthy infants, and for the first time reveal the orientation-specific longitudinal cortical surface expansion maps during the first postnatal year.
KW - Cortical folding
KW - Graph cuts
KW - Longitudinal development
KW - Orientation fields
KW - Surface expansion
UR - http://www.scopus.com/inward/record.url?scp=85048127329&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85048127329&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2018.8363666
DO - 10.1109/ISBI.2018.8363666
M3 - Conference contribution
VL - 2018-April
SP - 683
EP - 686
BT - 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018
PB - IEEE Computer Society
ER -