A cost-effective light emitting diode-acoustic system for preclinical ocular applications

Hojong Choi, Jaemyung Ryu, Jungyeol Yeom

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Opto-acoustic systems provide structural and functional information regarding biological tissues. Conventional opto-acoustic systems typically employ continuous or pulsed lasers as transmission sources. Compared to lasers, light emitting diodes (LEDs) are cost-effective and relatively portable excitation sources but are non, coherent. Therefore, in this study, a relatively low cost lens - a type of Ramsden eyepiece - was specially designed to theoretically calculate the illumination and achieve a constant brightness across the pupil of an eye. In order to verify the capability of the developed light-emitting diode-acoustic (LEDA) systems, we carried out experiments on bovine and bigeye tuna eyeball samples, which are of similar size to the human eye, using low frequency (10 MHz) and high frequency (25 MHz) ultrasound transducers. High frequency ultrasound transducers are able to provide higher spatial resolution compared to low frequency ultrasound transducers at the expense of penetration depth. Using the 10 MHz and 25 MHz ultrasound transducers, acceptable echo signals (3.82, 3.94, and 5.84 mV at 10 MHz and 282, 1557, 2356 mV at 25 MHz) from depth greater than 3 cm and 6 cm from the anterior surface of the eye were obtained. We thereby confirmed that the LEDA system using a pulsed LED with the designed Ramsden eyepiece lens, used in conjunction with low and high frequency ultrasound transducers, has the potential to be a cost-effective alternative method, while providing adequate acoustic signals from bovine and bigeye tuna ocular areas.

Original languageEnglish
Pages (from-to)59-68
Number of pages10
JournalCurrent Optics and Photonics
Volume2
Issue number1
DOIs
Publication statusPublished - 2018 Feb 1

Fingerprint

transducers
light emitting diodes
costs
acoustics
eyepieces
low frequencies
lenses
pupils
lasers
pulsed lasers
echoes
brightness
penetration
spatial resolution
illumination
high resolution
excitation

Keywords

  • Bigeye tuna
  • Bovine
  • Ramsden eyepiece
  • Ultrasound transducers

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

A cost-effective light emitting diode-acoustic system for preclinical ocular applications. / Choi, Hojong; Ryu, Jaemyung; Yeom, Jungyeol.

In: Current Optics and Photonics, Vol. 2, No. 1, 01.02.2018, p. 59-68.

Research output: Contribution to journalArticle

@article{d858f71e12b34c0ca91dfbdd9aa404f8,
title = "A cost-effective light emitting diode-acoustic system for preclinical ocular applications",
abstract = "Opto-acoustic systems provide structural and functional information regarding biological tissues. Conventional opto-acoustic systems typically employ continuous or pulsed lasers as transmission sources. Compared to lasers, light emitting diodes (LEDs) are cost-effective and relatively portable excitation sources but are non, coherent. Therefore, in this study, a relatively low cost lens - a type of Ramsden eyepiece - was specially designed to theoretically calculate the illumination and achieve a constant brightness across the pupil of an eye. In order to verify the capability of the developed light-emitting diode-acoustic (LEDA) systems, we carried out experiments on bovine and bigeye tuna eyeball samples, which are of similar size to the human eye, using low frequency (10 MHz) and high frequency (25 MHz) ultrasound transducers. High frequency ultrasound transducers are able to provide higher spatial resolution compared to low frequency ultrasound transducers at the expense of penetration depth. Using the 10 MHz and 25 MHz ultrasound transducers, acceptable echo signals (3.82, 3.94, and 5.84 mV at 10 MHz and 282, 1557, 2356 mV at 25 MHz) from depth greater than 3 cm and 6 cm from the anterior surface of the eye were obtained. We thereby confirmed that the LEDA system using a pulsed LED with the designed Ramsden eyepiece lens, used in conjunction with low and high frequency ultrasound transducers, has the potential to be a cost-effective alternative method, while providing adequate acoustic signals from bovine and bigeye tuna ocular areas.",
keywords = "Bigeye tuna, Bovine, Ramsden eyepiece, Ultrasound transducers",
author = "Hojong Choi and Jaemyung Ryu and Jungyeol Yeom",
year = "2018",
month = "2",
day = "1",
doi = "10.3807/COPP.2018.2.1.059",
language = "English",
volume = "2",
pages = "59--68",
journal = "Current Optics and Photonics",
issn = "2508-7266",
publisher = "Optical Society of Korea",
number = "1",

}

TY - JOUR

T1 - A cost-effective light emitting diode-acoustic system for preclinical ocular applications

AU - Choi, Hojong

AU - Ryu, Jaemyung

AU - Yeom, Jungyeol

PY - 2018/2/1

Y1 - 2018/2/1

N2 - Opto-acoustic systems provide structural and functional information regarding biological tissues. Conventional opto-acoustic systems typically employ continuous or pulsed lasers as transmission sources. Compared to lasers, light emitting diodes (LEDs) are cost-effective and relatively portable excitation sources but are non, coherent. Therefore, in this study, a relatively low cost lens - a type of Ramsden eyepiece - was specially designed to theoretically calculate the illumination and achieve a constant brightness across the pupil of an eye. In order to verify the capability of the developed light-emitting diode-acoustic (LEDA) systems, we carried out experiments on bovine and bigeye tuna eyeball samples, which are of similar size to the human eye, using low frequency (10 MHz) and high frequency (25 MHz) ultrasound transducers. High frequency ultrasound transducers are able to provide higher spatial resolution compared to low frequency ultrasound transducers at the expense of penetration depth. Using the 10 MHz and 25 MHz ultrasound transducers, acceptable echo signals (3.82, 3.94, and 5.84 mV at 10 MHz and 282, 1557, 2356 mV at 25 MHz) from depth greater than 3 cm and 6 cm from the anterior surface of the eye were obtained. We thereby confirmed that the LEDA system using a pulsed LED with the designed Ramsden eyepiece lens, used in conjunction with low and high frequency ultrasound transducers, has the potential to be a cost-effective alternative method, while providing adequate acoustic signals from bovine and bigeye tuna ocular areas.

AB - Opto-acoustic systems provide structural and functional information regarding biological tissues. Conventional opto-acoustic systems typically employ continuous or pulsed lasers as transmission sources. Compared to lasers, light emitting diodes (LEDs) are cost-effective and relatively portable excitation sources but are non, coherent. Therefore, in this study, a relatively low cost lens - a type of Ramsden eyepiece - was specially designed to theoretically calculate the illumination and achieve a constant brightness across the pupil of an eye. In order to verify the capability of the developed light-emitting diode-acoustic (LEDA) systems, we carried out experiments on bovine and bigeye tuna eyeball samples, which are of similar size to the human eye, using low frequency (10 MHz) and high frequency (25 MHz) ultrasound transducers. High frequency ultrasound transducers are able to provide higher spatial resolution compared to low frequency ultrasound transducers at the expense of penetration depth. Using the 10 MHz and 25 MHz ultrasound transducers, acceptable echo signals (3.82, 3.94, and 5.84 mV at 10 MHz and 282, 1557, 2356 mV at 25 MHz) from depth greater than 3 cm and 6 cm from the anterior surface of the eye were obtained. We thereby confirmed that the LEDA system using a pulsed LED with the designed Ramsden eyepiece lens, used in conjunction with low and high frequency ultrasound transducers, has the potential to be a cost-effective alternative method, while providing adequate acoustic signals from bovine and bigeye tuna ocular areas.

KW - Bigeye tuna

KW - Bovine

KW - Ramsden eyepiece

KW - Ultrasound transducers

UR - http://www.scopus.com/inward/record.url?scp=85045921768&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045921768&partnerID=8YFLogxK

U2 - 10.3807/COPP.2018.2.1.059

DO - 10.3807/COPP.2018.2.1.059

M3 - Article

AN - SCOPUS:85045921768

VL - 2

SP - 59

EP - 68

JO - Current Optics and Photonics

JF - Current Optics and Photonics

SN - 2508-7266

IS - 1

ER -