A Dramatic Acceleration of the Pauson-Khand Reaction by Trimethylamine N-Oxide

Nakcheol Jeong, Young Keun Chung, Bun Yeoul Lee, Sang Hee Lee, Sung Eun Yoo

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240 Citations (Scopus)

Abstract

The Pauson-Khand reaction (cocyclization of alkynes with alkenes and carbon monoxide by octacarbonyldicobalt leading to cyclopentenones) was greatly accelerated by trimethylamine N-oxide in the presence of oxygen in dichloromethane at 0 °C to room temperature. This process worked quite effectively for both intermolecular and intramolecular reactions.

Original languageEnglish
Pages (from-to)204-206
Number of pages3
JournalSynlett
Volume1991
Issue number3
DOIs
Publication statusPublished - 1991 Mar 1
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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    Jeong, N., Chung, Y. K., Lee, B. Y., Lee, S. H., & Yoo, S. E. (1991). A Dramatic Acceleration of the Pauson-Khand Reaction by Trimethylamine N-Oxide. Synlett, 1991(3), 204-206. https://doi.org/10.1055/s-1991-20681