A far-red, photo- and bio-stable fluorescent marker selective to the endoplasmic reticulum and its application to tunicamycin-treated HeLa cells

Hye Ri Kim, Rajesh Kumar, Woori Kim, Jae Hong Lee, Myungkoo Suh, Amit Sharma, Chang Hoe Kim, Chulhun Kang, Jong Seung Kim

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Herein, we developed an ER selective fluorescent ERp that exhibited a sharp fluorescence emission in the far-red region and high photo- and bio-stability in biological milieu. Its emission is insensitive to pH change and localized in the ER of the cells. Furthermore, it successfully demonstrated that the ER membrane is rapidly reorganized in the perinuclear region by an ER stress inducer, tunicamycin.

Original languageEnglish
Pages (from-to)7134-7137
Number of pages4
JournalChemical Communications
Volume52
Issue number44
DOIs
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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