A fluorescent chemosensor for Hg2+ and Cd2+ ions in aqueous medium under physiological ph and its applications in imaging living cells

Shubhra B. Maity, Saikat Banerjee, Kyoung Sunwoo, Jong Seung Kim, Parimal K. Bharadwaj

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

A new BODIPY derivative with 2,2-(ethane-1,2-diylbis(oxy))bis(N,N-bis(pyridine-2-ylmethyl)aniline unit as the metal receptor has been designed and synthesized. The dye selectively detects either Cd2+ or Hg2+ ions in the presence of hosts of other biologically important and environmentally relevant metal ions in aqueous medium at physiological pH. Binding of metal ions causes a change in the emission behavior of the dye from weakly fluorescent to highly fluorescent. Confocal microscopic experiments validate that the dye can be used to identify changes in either Hg2+ or Cd2+ levels in living cells.

Original languageEnglish
Pages (from-to)3929-3936
Number of pages8
JournalInorganic Chemistry
Volume54
Issue number8
DOIs
Publication statusPublished - 2015 Apr 20

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

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