A fluorescent chemosensor for Hg<sup>2+</sup> and Cd<sup>2+</sup> ions in aqueous medium under physiological ph and its applications in imaging living cells

Shubhra B. Maity, Saikat Banerjee, Kyoung Sunwoo, Jong Seung Kim, Parimal K. Bharadwaj

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

A new BODIPY derivative with 2,2-(ethane-1,2-diylbis(oxy))bis(N,N-bis(pyridine-2-ylmethyl)aniline unit as the metal receptor has been designed and synthesized. The dye selectively detects either Cd<sup>2+</sup> or Hg<sup>2+</sup> ions in the presence of hosts of other biologically important and environmentally relevant metal ions in aqueous medium at physiological pH. Binding of metal ions causes a change in the emission behavior of the dye from weakly fluorescent to highly fluorescent. Confocal microscopic experiments validate that the dye can be used to identify changes in either Hg<sup>2+</sup> or Cd<sup>2+</sup> levels in living cells.

Original languageEnglish
Pages (from-to)3929-3936
Number of pages8
JournalInorganic Chemistry
Volume54
Issue number8
DOIs
Publication statusPublished - 2015 Apr 20

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Metal ions
Coloring Agents
dyes
Metals
Cells
Ions
Imaging techniques
Ethane
metal ions
Fluorescent Dyes
ions
aniline
Derivatives
ethane
pyridines
causes
Experiments
metals
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
pyridine

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Physical and Theoretical Chemistry

Cite this

A fluorescent chemosensor for Hg<sup>2+</sup> and Cd<sup>2+</sup> ions in aqueous medium under physiological ph and its applications in imaging living cells. / Maity, Shubhra B.; Banerjee, Saikat; Sunwoo, Kyoung; Kim, Jong Seung; Bharadwaj, Parimal K.

In: Inorganic Chemistry, Vol. 54, No. 8, 20.04.2015, p. 3929-3936.

Research output: Contribution to journalArticle

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