A fluorescent chemosensor for Hg2+ and Cd2+ ions in aqueous medium under physiological ph and its applications in imaging living cells

Shubhra B. Maity; Saikat Banerjee; Kyoung Sunwoo; Jong Seung Kim; Parimal K. Bharadwaj

doi:10.1021/acs.inorgchem.5b00106

A fluorescent chemosensor for Hg²⁺ and Cd²⁺ ions in aqueous medium under physiological ph and its applications in imaging living cells

Shubhra B. Maity, Saikat Banerjee, Kyoung Sunwoo, Jong Seung Kim, Parimal K. Bharadwaj

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

A new BODIPY derivative with 2,2-(ethane-1,2-diylbis(oxy))bis(N,N-bis(pyridine-2-ylmethyl)aniline unit as the metal receptor has been designed and synthesized. The dye selectively detects either Cd²⁺ or Hg²⁺ ions in the presence of hosts of other biologically important and environmentally relevant metal ions in aqueous medium at physiological pH. Binding of metal ions causes a change in the emission behavior of the dye from weakly fluorescent to highly fluorescent. Confocal microscopic experiments validate that the dye can be used to identify changes in either Hg²⁺ or Cd²⁺ levels in living cells.

Original language	English
Pages (from-to)	3929-3936
Number of pages	8
Journal	Inorganic Chemistry
Volume	54
Issue number	8
DOIs	https://doi.org/10.1021/acs.inorgchem.5b00106
Publication status	Published - 2015 Apr 20

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry

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abstract = "A new BODIPY derivative with 2,2-(ethane-1,2-diylbis(oxy))bis(N,N-bis(pyridine-2-ylmethyl)aniline unit as the metal receptor has been designed and synthesized. The dye selectively detects either Cd2+ or Hg2+ ions in the presence of hosts of other biologically important and environmentally relevant metal ions in aqueous medium at physiological pH. Binding of metal ions causes a change in the emission behavior of the dye from weakly fluorescent to highly fluorescent. Confocal microscopic experiments validate that the dye can be used to identify changes in either Hg2+ or Cd2+ levels in living cells.",

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AU - Kim, Jong Seung

AU - Bharadwaj, Parimal K.

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A fluorescent chemosensor for Hg²⁺ and Cd²⁺ ions in aqueous medium under physiological ph and its applications in imaging living cells

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