A fluorescent nanobiosensor for the facile analysis of m6A RNA demethylase activity

Seo Hee Yim, Hyung Jin Cha, Se Jin Park, Yeajee Yim, Jae Sung Woo, Dal Hee Min

Research output: Contribution to journalArticle

Abstract

RNA demethylase has recently been known to be associated with cancer development but its selective inhibitors as anti-cancer agents have rarely been investigated to date. Herein, we have developed a fluorescent nanobiosensor which enables efficient quantitative analysis of RNA demethylase ALKBH5 activity and shows a high potential for robust inhibitor screening.

Original languageEnglish
Pages (from-to)4716-4719
Number of pages4
JournalChemical Communications
Volume56
Issue number34
DOIs
Publication statusPublished - 2020 Apr 30

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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