A hemodynamic study on a marginal cell depletion layer of blood flow inside a microchannel

Cheol Woo Park, Sehyun Shin, Gyu Man Kim, Jin Hong Jang, Yoon Hee Gu

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Biological flows, especially blood flow, have attracted a great deal of attention from fluid engineering and hemodynamic investigation fields with advances in bio-technology. The flow of blood carries dissolved gases, nutrients, hormones, and metabolic waste through the circulatory system in the human body. In the present study, the characteristics of blood flow inside a microchannel are investigated by using a micro-particle image velocimetry (micro-PIV) and an optical image processing technique. The motion of red blood cells (RBCs) was visualized with a high-speed CCD camera. The microchannel is made of polydimethylsiloxane (PDMS) material and a slide-glass is attached to the top. The thickness of the margin cell depletion layer is calculated from an acquired raw image through the image processing method, with variations in microchannel width.

Original languageEnglish
Pages (from-to)863-866
Number of pages4
JournalKey Engineering Materials
Volume326-328 I
Publication statusPublished - 2006 Dec 6
Externally publishedYes

Keywords

  • Blood flow
  • Cell depletion layer
  • Micro-PIV
  • Microchannel
  • RBCs

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

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