A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue

Na Young Baek, Cheol Ho Heo, Chang Su Lim, Goutam Masanta, Bong-Rae Cho, Hwan Myung Kim

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn 2+ and can selectively detect mitochondrial Zn 2+ in a rat hippocampal slice at a depth of 100-200 μm by using two-photon microscopy. This journal is

Original languageEnglish
Pages (from-to)4546-4548
Number of pages3
JournalChemical Communications
Volume48
Issue number38
DOIs
Publication statusPublished - 2012 May 14

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Fluorescent Dyes
Photons
Zinc
Ions
Tissue
Rats
Microscopy
Microscopic examination
Fluorescence

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue. / Baek, Na Young; Heo, Cheol Ho; Lim, Chang Su; Masanta, Goutam; Cho, Bong-Rae; Kim, Hwan Myung.

In: Chemical Communications, Vol. 48, No. 38, 14.05.2012, p. 4546-4548.

Research output: Contribution to journalArticle

Baek, Na Young ; Heo, Cheol Ho ; Lim, Chang Su ; Masanta, Goutam ; Cho, Bong-Rae ; Kim, Hwan Myung. / A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue. In: Chemical Communications. 2012 ; Vol. 48, No. 38. pp. 4546-4548.
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