A highly sensitive two-photon fluorescent probe for mitochondrial zinc ions in living tissue

Na Young Baek, Cheol Ho Heo, Chang Su Lim, Goutam Masanta, Bong Rae Cho, Hwan Myung Kim

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

We report a highly sensitive two-photon probe (SZn2-Mito) which shows a 70-fold two-photon excited fluorescence enhancement in response to Zn 2+ and can selectively detect mitochondrial Zn2+ in a rat hippocampal slice at a depth of 100-200 μm by using two-photon microscopy.

Original languageEnglish
Pages (from-to)4546-4548
Number of pages3
JournalChemical Communications
Volume48
Issue number38
DOIs
Publication statusPublished - 2012 May 14

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ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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