A Mach-Zehnder interferometer based on silicon oxides for biosensor applications

Jongin Hong, Jung Sung Choi, Gayoung Han, Jae Kwang Kang, Chang Min Kim, Tae Song Kim, Dae Sung Yoon

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Integrated optical devices have been increasingly interested in biosensor applications including environmental pollution, biological process and medical diagnostics. Integrated optics allows high-detection sensitivity to be achieved using optical transduction techniques in a microfluidic format. Among different transduction techniques, a Mach-Zehnder interferometer (MZI) has advantage of its inherent high sensitivity and accuracy. The evanescent wave of an optical waveguide interacts with an adjacent layer, and this can be the basis of the recognition of biomolecules. In recent years, silicon dielectrics as potential materials have been attracted in an integrated optics. The refractive index of these silicon-based materials can be easily adjusted continuously over a wide range between 1.45 (SiO2) and 1.97 (SiO). This comes to be very attractive in terms of design and fabrication of single-mode waveguides. In this article, we tried to realize the Mach-Zehnder interferometer sensor based on silicon oxides, and the refractive index of the oxides was controlled by the oxygen concentration to achieve the single-mode behavior of a total internal reflection (TIR) waveguide. We have performed to verify the feasibility of the MZI sensor for the direct detection of immunoreactions.

Original languageEnglish
Pages (from-to)97-103
Number of pages7
JournalAnalytica Chimica Acta
Volume573-574
DOIs
Publication statusPublished - 2006 Jul 28
Externally publishedYes

Fingerprint

Mach-Zehnder interferometers
Silicon oxides
Biosensing Techniques
Silicon
interferometer
Biosensors
Oxides
silicon
Refractometry
Integrated optics
oxide
refractive index
Refractive index
Waveguides
sensor
Biological Phenomena
Optical Devices
Environmental Pollution
Microfluidics
Sensors

Keywords

  • Biosensor
  • Immunoreaction
  • Mach-Zehnder interferometer
  • Single-mode
  • Waveguide

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy

Cite this

A Mach-Zehnder interferometer based on silicon oxides for biosensor applications. / Hong, Jongin; Choi, Jung Sung; Han, Gayoung; Kang, Jae Kwang; Kim, Chang Min; Kim, Tae Song; Yoon, Dae Sung.

In: Analytica Chimica Acta, Vol. 573-574, 28.07.2006, p. 97-103.

Research output: Contribution to journalArticle

Hong, Jongin ; Choi, Jung Sung ; Han, Gayoung ; Kang, Jae Kwang ; Kim, Chang Min ; Kim, Tae Song ; Yoon, Dae Sung. / A Mach-Zehnder interferometer based on silicon oxides for biosensor applications. In: Analytica Chimica Acta. 2006 ; Vol. 573-574. pp. 97-103.
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