A mesoporous, silica-immobilized-nanoparticle colorimetric chemosensor for the detection of nerve agents

Hyun Jung Kim, Ji Ha Lee, Hyejin Lee, Jae Hong Lee, Joung Hae Lee, Jong Hwa Jung, Jong Seung Kim

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

A new and an easy-to-make colorimetric azo-pyridine, 1, and its recyclable mesoporous silica-immobilized nanoparticles for nerve-agent detection are synthesized. The binding site, comprising an azo-pyridine moiety, is capable of selectively sensing diethylchlorophosphate (DCP), one of the nerve-agent mimics of chemical-warfare agents, over a series of other phosphate compounds. Compound 1 shows ratiometric changes in absorption spectroscopy to the extent of a 60 nm red-shift upon the addition of DCP, mainly due to a change in the intramolecular charge transfer (ICT) in 1 . The color change of receptor 1 from yellow to red in the concentration region = 1.0 × 10 -6 M is sufficient for the selective detection of the DCP nerve-agent mimic by the naked eye. With regards to solid-phase application, mesoporous silica nanoparticles using 1 ( MSIAP ) are also prepared using a sol-gel grafting reaction. The color of the MSIAP also changes from red to yellow when dipped into an aqueous DCP solution, and turns back to red when treated with NaOH solution, with nontoxic diethylphosphoric acid being given off. The absorption changes of MSIAP in the presence of DCP are consistent within the 3-9 pH range.

Original languageEnglish
Pages (from-to)4035-4040
Number of pages6
JournalAdvanced Functional Materials
Volume21
Issue number21
DOIs
Publication statusPublished - 2011 Nov 8

Fingerprint

nerves
Silicon Dioxide
Silica
Nanoparticles
silicon dioxide
nanoparticles
Pyridine
pyridines
chemical warfare
Chemical warfare
Color
color
Chemical Warfare Agents
Binding sites
Absorption spectroscopy
red shift
Sol-gels
solid phases
Charge transfer
phosphates

ASJC Scopus subject areas

  • Biomaterials
  • Electrochemistry
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

A mesoporous, silica-immobilized-nanoparticle colorimetric chemosensor for the detection of nerve agents. / Kim, Hyun Jung; Lee, Ji Ha; Lee, Hyejin; Lee, Jae Hong; Lee, Joung Hae; Jung, Jong Hwa; Kim, Jong Seung.

In: Advanced Functional Materials, Vol. 21, No. 21, 08.11.2011, p. 4035-4040.

Research output: Contribution to journalArticle

Kim, Hyun Jung ; Lee, Ji Ha ; Lee, Hyejin ; Lee, Jae Hong ; Lee, Joung Hae ; Jung, Jong Hwa ; Kim, Jong Seung. / A mesoporous, silica-immobilized-nanoparticle colorimetric chemosensor for the detection of nerve agents. In: Advanced Functional Materials. 2011 ; Vol. 21, No. 21. pp. 4035-4040.
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