A microfluidic device with integrated impedance detection for λ-DNA

Myung Il Park, Jonging Hong, Dae Sung Yoon, Chong Ook Park, Geunbae Im

Research output: Contribution to journalConference article

2 Citations (Scopus)

Abstract

The large optical detection systems that are typically utilized at present may not be able to reach their full potential as portable analysis tools. Accurate, early, and fast diagnosis for many diseases requires the direct detection of biomolecules such as DNA, proteins, and cells. In this research, a glass microchip with integrated microelectrodes has been fabricated, and the performance of electrochemical impedance detection was investigated for the biomolecules. We have used label-free λ-DNA as a sample biomolecule. By changing the distance between microelectrodes, the significant difference between DW and the TE buffer solution is obtained from the impedance-frequency measurements. In addition, the comparison for the impedance magnitude of DW, the TE buffer, and λ-DNA at the same distance was analyzed.

Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalMaterials Research Society Symposium - Proceedings
Volume773
DOIs
Publication statusPublished - 2003
EventBiomicroelectromechanical Systems (BioMEMS) - San Francisco, CA, United States
Duration: 2003 Apr 222003 Apr 25

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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