A microfluidic device with integrated impedance detection for λ-DNA

Myung Il Park, Jonging Hong, Dae Sung Yoon, Chong Ook Park, Geunbae Im

Research output: Contribution to journalConference article

2 Citations (Scopus)

Abstract

The large optical detection systems that are typically utilized at present may not be able to reach their full potential as portable analysis tools. Accurate, early, and fast diagnosis for many diseases requires the direct detection of biomolecules such as DNA, proteins, and cells. In this research, a glass microchip with integrated microelectrodes has been fabricated, and the performance of electrochemical impedance detection was investigated for the biomolecules. We have used label-free λ-DNA as a sample biomolecule. By changing the distance between microelectrodes, the significant difference between DW and the TE buffer solution is obtained from the impedance-frequency measurements. In addition, the comparison for the impedance magnitude of DW, the TE buffer, and λ-DNA at the same distance was analyzed.

Original languageEnglish
Pages (from-to)149-154
Number of pages6
JournalMaterials Research Society Symposium - Proceedings
Volume773
Publication statusPublished - 2003 Dec 1
Externally publishedYes
EventBiomicroelectromechanical Systems (BioMEMS) - San Francisco, CA, United States
Duration: 2003 Apr 222003 Apr 25

Fingerprint

microfluidic devices
Biomolecules
Microfluidics
DNA
deoxyribonucleic acid
Microelectrodes
impedance
Buffers
buffers
frequency measurement
Labels
proteins
Proteins
Glass
glass
cells

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

A microfluidic device with integrated impedance detection for λ-DNA. / Park, Myung Il; Hong, Jonging; Yoon, Dae Sung; Park, Chong Ook; Im, Geunbae.

In: Materials Research Society Symposium - Proceedings, Vol. 773, 01.12.2003, p. 149-154.

Research output: Contribution to journalConference article

Park, Myung Il ; Hong, Jonging ; Yoon, Dae Sung ; Park, Chong Ook ; Im, Geunbae. / A microfluidic device with integrated impedance detection for λ-DNA. In: Materials Research Society Symposium - Proceedings. 2003 ; Vol. 773. pp. 149-154.
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