A monolithic and flexible fluoropolymer film microreactor for organic synthesis applications

Jin Oh Kim, Heejin Kim, Dong Hyeon Ko, Kyoung Ik Min, Do Jin Im, Soo Young Park, Dong Pyo Kim

Research output: Contribution to journalArticle

14 Citations (Scopus)


A photocurable and viscous fluoropolymer with chemical stability is a highly desirable material for fabrication of microchemical devices. Lack of a reliable fabrication method, however, limits actual applications for organic reactions. Herein, we report fabrication of a monolithic and flexible fluoropolymer film microreactor and its use as a new microfluidic platform. The fabrication involves facile soft lithography techniques that enable partial curing of thin laminates, which can be readily bonded by conformal contact without any external forces. We demonstrate fabrication of various functional channels (~300 μm thick) such as those embedded with either a herringbone micromixer pattern or a droplet generator. Organic reactions under strongly acidic and basic conditions can be carried out in this film microreactor even at elevated temperature with excellent reproducibility. In particular, the transparent film microreactor with good deformability could be wrapped around a light-emitting lamp for close contact with the light source for efficient photochemical reactions with visible light, which demonstrates easy integration with optical components for functional miniaturized systems. This journal is

Original languageEnglish
Pages (from-to)4270-4276
Number of pages7
JournalLab on a Chip
Issue number21
Publication statusPublished - 2014 Nov 7
Externally publishedYes


ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

Cite this

Kim, J. O., Kim, H., Ko, D. H., Min, K. I., Im, D. J., Park, S. Y., & Kim, D. P. (2014). A monolithic and flexible fluoropolymer film microreactor for organic synthesis applications. Lab on a Chip, 14(21), 4270-4276. https://doi.org/10.1039/c4lc00748d