A new in vivo-mimic angiogenesis MI-crofluidc platfrom for the study of cell encapsulation based cell therapy

Choong Kim, Min Cheol Kim, Seok Chung, H. Harry Asada, Roger D. Kamm

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we have developed a novel in vitro angiogenesis on a chip to identify potential molecular targets, secreted from cell encapsulated beads; augmenting, altering and blocking endothelial cell responses, and to enable preliminary screening before transplantation. We confirmed that growth factors secreted from the encapsulated cells in CE beads were able to induce ECs migration and form lumen-like structures in the collagen scaffold.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages783-785
Number of pages3
Publication statusPublished - 2011
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: 2011 Oct 22011 Oct 6

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume2

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period11/10/211/10/6

Keywords

  • Angiogenesis
  • Cell encapsulation based cell therapy

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • Cite this

    Kim, C., Kim, M. C., Chung, S., Harry Asada, H., & Kamm, R. D. (2011). A new in vivo-mimic angiogenesis MI-crofluidc platfrom for the study of cell encapsulation based cell therapy. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 (pp. 783-785). (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; Vol. 2).