A new index of the dose homogeneity for treatment planning

Myonggeun Yoon; Dongho Shin; Sung Yong Park; Se Byeong Lee; Tae Hyun Kim; Dae Yong Kim; Kwan Ho Cho

doi:10.1007/978-3-540-36841-0_514

A new index of the dose homogeneity for treatment planning

Myonggeun Yoon, Dongho Shin, Sung Yong Park, Se Byeong Lee, Tae Hyun Kim, Dae Yong Kim, Kwan Ho Cho

School of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The goal of this study is to develop new indices, which effectively evaluate dose homogeneity of intensitymodulated radiotherapy (IMRT) treatment plans with dose– volume histogram (DVH). The newly defined homogeneity indices for assessing dose homogeneity in a target volume, named s-index and n-index, were developed using a normalized differential-DVH (dDVH) and functional approximation of DVH, respectively. Although both indices have been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity, the results showed the sindex is more consistent method for quantifying the degree of homogeneity. The s-index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for 16 brain tumor patients at out institution. A guideline of the treatment plan based on s-index for dose homogeneity is discussed with relation to equivalent uniform dose (EUD).

Original language	English
Title of host publication	IFMBE Proceedings
Editors	Sun I. Kim, Tae Suk Suh
Publisher	Springer Verlag
Pages	2043-2046
Number of pages	4
Edition	1
ISBN (Print)	9783540368397
DOIs	https://doi.org/10.1007/978-3-540-36841-0_514
Publication status	Published - 2007
Event	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: 2006 Aug 27 → 2006 Sep 1

Publication series

Name	IFMBE Proceedings
Number	1
Volume	14
ISSN (Print)	1680-0737
ISSN (Electronic)	1433-9277

Other

Other	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country	Korea, Republic of
City	Seoul
Period	06/8/27 → 06/9/1

Keywords

Equivalent uniform dose
Homogeneity index
IMRT
Target-volume DVH

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

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A new index of the dose homogeneity for treatment planning. / Yoon, Myonggeun; Shin, Dongho; Park, Sung Yong; Lee, Se Byeong; Kim, Tae Hyun; Kim, Dae Yong; Cho, Kwan Ho.

IFMBE Proceedings. ed. / Sun I. Kim; Tae Suk Suh. 1. ed. Springer Verlag, 2007. p. 2043-2046 (IFMBE Proceedings; Vol. 14, No. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yoon, M, Shin, D, Park, SY, Lee, SB, Kim, TH, Kim, DY & Cho, KH 2007, A new index of the dose homogeneity for treatment planning. in SI Kim & TS Suh (eds), IFMBE Proceedings. 1 edn, IFMBE Proceedings, no. 1, vol. 14, Springer Verlag, pp. 2043-2046, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 06/8/27. https://doi.org/10.1007/978-3-540-36841-0_514

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note = "Publisher Copyright: {\textcopyright} International Federation for Medical and Biological Engineering 2007. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.; 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 ; Conference date: 27-08-2006 Through 01-09-2006",

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AB - The goal of this study is to develop new indices, which effectively evaluate dose homogeneity of intensitymodulated radiotherapy (IMRT) treatment plans with dose– volume histogram (DVH). The newly defined homogeneity indices for assessing dose homogeneity in a target volume, named s-index and n-index, were developed using a normalized differential-DVH (dDVH) and functional approximation of DVH, respectively. Although both indices have been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity, the results showed the sindex is more consistent method for quantifying the degree of homogeneity. The s-index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for 16 brain tumor patients at out institution. A guideline of the treatment plan based on s-index for dose homogeneity is discussed with relation to equivalent uniform dose (EUD).

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