Abstract
The goal of this study is to develop new indices, which effectively evaluate dose homogeneity of intensitymodulated radiotherapy (IMRT) treatment plans with dose– volume histogram (DVH). The newly defined homogeneity indices for assessing dose homogeneity in a target volume, named s-index and n-index, were developed using a normalized differential-DVH (dDVH) and functional approximation of DVH, respectively. Although both indices have been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity, the results showed the sindex is more consistent method for quantifying the degree of homogeneity. The s-index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for 16 brain tumor patients at out institution. A guideline of the treatment plan based on s-index for dose homogeneity is discussed with relation to equivalent uniform dose (EUD).
| Original language | English |
|---|---|
| Title of host publication | IFMBE Proceedings |
| Publisher | Springer Verlag |
| Pages | 2043-2046 |
| Number of pages | 4 |
| Volume | 14 |
| Edition | 1 |
| Publication status | Published - 2007 |
| Externally published | Yes |
| Event | 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: 2006 Aug 27 → 2006 Sep 1 |
Other
| Other | 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 |
|---|---|
| Country | Korea, Republic of |
| City | Seoul |
| Period | 06/8/27 → 06/9/1 |
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Keywords
- Equivalent uniform dose
- Homogeneity index
- IMRT
- Target-volume DVH
ASJC Scopus subject areas
- Biomedical Engineering
- Bioengineering
Cite this
A new index of the dose homogeneity for treatment planning. / Yoon, Myonggeun; Shin, Dongho; Park, Sung Yong; Lee, Se Byeong; Kim, Tae Hyun; Kim, Dae Yong; Cho, Kwan Ho.
IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. p. 2043-2046.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - A new index of the dose homogeneity for treatment planning
AU - Yoon, Myonggeun
AU - Shin, Dongho
AU - Park, Sung Yong
AU - Lee, Se Byeong
AU - Kim, Tae Hyun
AU - Kim, Dae Yong
AU - Cho, Kwan Ho
PY - 2007
Y1 - 2007
N2 - The goal of this study is to develop new indices, which effectively evaluate dose homogeneity of intensitymodulated radiotherapy (IMRT) treatment plans with dose– volume histogram (DVH). The newly defined homogeneity indices for assessing dose homogeneity in a target volume, named s-index and n-index, were developed using a normalized differential-DVH (dDVH) and functional approximation of DVH, respectively. Although both indices have been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity, the results showed the sindex is more consistent method for quantifying the degree of homogeneity. The s-index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for 16 brain tumor patients at out institution. A guideline of the treatment plan based on s-index for dose homogeneity is discussed with relation to equivalent uniform dose (EUD).
AB - The goal of this study is to develop new indices, which effectively evaluate dose homogeneity of intensitymodulated radiotherapy (IMRT) treatment plans with dose– volume histogram (DVH). The newly defined homogeneity indices for assessing dose homogeneity in a target volume, named s-index and n-index, were developed using a normalized differential-DVH (dDVH) and functional approximation of DVH, respectively. Although both indices have been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity, the results showed the sindex is more consistent method for quantifying the degree of homogeneity. The s-index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for 16 brain tumor patients at out institution. A guideline of the treatment plan based on s-index for dose homogeneity is discussed with relation to equivalent uniform dose (EUD).
KW - Equivalent uniform dose
KW - Homogeneity index
KW - IMRT
KW - Target-volume DVH
UR - http://www.scopus.com/inward/record.url?scp=84958292052&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84958292052&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84958292052
VL - 14
SP - 2043
EP - 2046
BT - IFMBE Proceedings
PB - Springer Verlag
ER -