A new MEMS neural probe system integrated with push-pull microfluidic channels and biosensors for real-time monitoring of neurochemicals

Uikyu Chae, Hyoguen Shin, Hyunjoo Jenny Lee, Jungpyo Lee, Nakwon Choi, Yi Jae Lee, Soo Hyun Lee, Jiwan Woo, Yakdol Cho, Eui Sung Yoon, Hyun-Yong Yu, Il Joo Cho

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We present a new MEMS neural probe integrated with two microfluidic channels, a mixer, and biosensors for real-time monitoring of neurochemicals and neural activities. The microfluidic channels for push-pull operation of fluids enable infusion of drugs and extraction of brain fluid at the same time. Also, we can simultaneously monitor neural activities modulated by the infused drug. The real-time monitoring of neurochemicals using the monolithically integrated sensors is a new concept we propose which is enabled through the MEMS technology. The proposed system will provide an important new set of information for brain disease investigation and functional brain-mapping.

Original languageEnglish
Title of host publicationMEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages329-332
Number of pages4
Volume2016-February
ISBN (Electronic)9781509019731
DOIs
Publication statusPublished - 2016 Feb 26
Event29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016 - Shanghai, China
Duration: 2016 Jan 242016 Jan 28

Other

Other29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016
CountryChina
CityShanghai
Period16/1/2416/1/28

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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    Chae, U., Shin, H., Lee, H. J., Lee, J., Choi, N., Lee, Y. J., Lee, S. H., Woo, J., Cho, Y., Yoon, E. S., Yu, H-Y., & Cho, I. J. (2016). A new MEMS neural probe system integrated with push-pull microfluidic channels and biosensors for real-time monitoring of neurochemicals. In MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems (Vol. 2016-February, pp. 329-332). [7421627] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2016.7421627