Abstract
DNA molecules have been widely recognized as promising building blocks for constructing functional nanostructures with two main features, that is, self-assembly and rich chemical functionality. The intrinsic feature size of DNA makes it attractive for creating versatile nanostructures. Moreover, the ease of access to tune the surface of DNA by chemical functionalization offers numerous opportunities for many applications. Herein, a simple yet robust strategy is developed to yield the self-assembly of DNA by exploiting controlled evaporative assembly of DNA solution in a unique confined geometry. Intriguingly, depending on the concentration of DNA solution, highly aligned nanostructured fibrillar-like arrays and well-positioned concentric ring-like superstructures composed of DNAs are formed. Subsequently, the ring-like negatively charged DNA superstructures are employed as template to produce conductive organic nanowires on a silicon substrate by complexing with a positively charged conjugated polyelectrolyte poly[9,9-bis(6'-N,N,N-trimethylammoniumhexyl)fluorene dibromide] (PF2) through the strong electrostatic interaction. Finally, a monolithic integration of aligned arrays of DNA-templated PF2 nanowires to yield two DNA/PF2-based devices is demonstrated. It is envisioned that this strategy can be readily extended to pattern other biomolecules and may render a broad range of potential applications from the nucleotide sequence and hybridization as recognition events to transducing elements in chemical sensors.
| Original language | English |
|---|---|
| Pages (from-to) | 4254-4263 |
| Number of pages | 10 |
| Journal | Small (Weinheim an der Bergstrasse, Germany) |
| Volume | 12 |
| Issue number | 31 |
| DOIs | |
| Publication status | Published - 2016 Aug 1 |
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Keywords
- conjugated polymers
- drying-mediated assembly
- salmon sperm DNA
- surface patterning
ASJC Scopus subject areas
- Biotechnology
- Biomaterials
- Chemistry(all)
- Materials Science(all)
Cite this
A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires. / Bae, Dong Geun; Jeong, Ji Eun; Kang, Seok Hee; Byun, Myunghwan; Han, Dong Wook; Lin, Zhiqun; Woo, Han Young; Hong, Suck Won.
In: Small (Weinheim an der Bergstrasse, Germany), Vol. 12, No. 31, 01.08.2016, p. 4254-4263.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires
AU - Bae, Dong Geun
AU - Jeong, Ji Eun
AU - Kang, Seok Hee
AU - Byun, Myunghwan
AU - Han, Dong Wook
AU - Lin, Zhiqun
AU - Woo, Han Young
AU - Hong, Suck Won
PY - 2016/8/1
Y1 - 2016/8/1
N2 - DNA molecules have been widely recognized as promising building blocks for constructing functional nanostructures with two main features, that is, self-assembly and rich chemical functionality. The intrinsic feature size of DNA makes it attractive for creating versatile nanostructures. Moreover, the ease of access to tune the surface of DNA by chemical functionalization offers numerous opportunities for many applications. Herein, a simple yet robust strategy is developed to yield the self-assembly of DNA by exploiting controlled evaporative assembly of DNA solution in a unique confined geometry. Intriguingly, depending on the concentration of DNA solution, highly aligned nanostructured fibrillar-like arrays and well-positioned concentric ring-like superstructures composed of DNAs are formed. Subsequently, the ring-like negatively charged DNA superstructures are employed as template to produce conductive organic nanowires on a silicon substrate by complexing with a positively charged conjugated polyelectrolyte poly[9,9-bis(6'-N,N,N-trimethylammoniumhexyl)fluorene dibromide] (PF2) through the strong electrostatic interaction. Finally, a monolithic integration of aligned arrays of DNA-templated PF2 nanowires to yield two DNA/PF2-based devices is demonstrated. It is envisioned that this strategy can be readily extended to pattern other biomolecules and may render a broad range of potential applications from the nucleotide sequence and hybridization as recognition events to transducing elements in chemical sensors.
AB - DNA molecules have been widely recognized as promising building blocks for constructing functional nanostructures with two main features, that is, self-assembly and rich chemical functionality. The intrinsic feature size of DNA makes it attractive for creating versatile nanostructures. Moreover, the ease of access to tune the surface of DNA by chemical functionalization offers numerous opportunities for many applications. Herein, a simple yet robust strategy is developed to yield the self-assembly of DNA by exploiting controlled evaporative assembly of DNA solution in a unique confined geometry. Intriguingly, depending on the concentration of DNA solution, highly aligned nanostructured fibrillar-like arrays and well-positioned concentric ring-like superstructures composed of DNAs are formed. Subsequently, the ring-like negatively charged DNA superstructures are employed as template to produce conductive organic nanowires on a silicon substrate by complexing with a positively charged conjugated polyelectrolyte poly[9,9-bis(6'-N,N,N-trimethylammoniumhexyl)fluorene dibromide] (PF2) through the strong electrostatic interaction. Finally, a monolithic integration of aligned arrays of DNA-templated PF2 nanowires to yield two DNA/PF2-based devices is demonstrated. It is envisioned that this strategy can be readily extended to pattern other biomolecules and may render a broad range of potential applications from the nucleotide sequence and hybridization as recognition events to transducing elements in chemical sensors.
KW - conjugated polymers
KW - drying-mediated assembly
KW - salmon sperm DNA
KW - surface patterning
UR - http://www.scopus.com/inward/record.url?scp=84981525068&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84981525068&partnerID=8YFLogxK
U2 - 10.1002/smll.201601346
DO - 10.1002/smll.201601346
M3 - Article
C2 - 27351291
AN - SCOPUS:84981525068
VL - 12
SP - 4254
EP - 4263
JO - Small
JF - Small
SN - 1613-6810
IS - 31
ER -