A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires

Dong Geun Bae, Ji Eun Jeong, Seok Hee Kang, Myunghwan Byun, Dong Wook Han, Zhiqun Lin, Han Young Woo, Suck Won Hong

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

DNA molecules have been widely recognized as promising building blocks for constructing functional nanostructures with two main features, that is, self-assembly and rich chemical functionality. The intrinsic feature size of DNA makes it attractive for creating versatile nanostructures. Moreover, the ease of access to tune the surface of DNA by chemical functionalization offers numerous opportunities for many applications. Herein, a simple yet robust strategy is developed to yield the self-assembly of DNA by exploiting controlled evaporative assembly of DNA solution in a unique confined geometry. Intriguingly, depending on the concentration of DNA solution, highly aligned nanostructured fibrillar-like arrays and well-positioned concentric ring-like superstructures composed of DNAs are formed. Subsequently, the ring-like negatively charged DNA superstructures are employed as template to produce conductive organic nanowires on a silicon substrate by complexing with a positively charged conjugated polyelectrolyte poly[9,9-bis(6'-N,N,N-trimethylammoniumhexyl)fluorene dibromide] (PF2) through the strong electrostatic interaction. Finally, a monolithic integration of aligned arrays of DNA-templated PF2 nanowires to yield two DNA/PF2-based devices is demonstrated. It is envisioned that this strategy can be readily extended to pattern other biomolecules and may render a broad range of potential applications from the nucleotide sequence and hybridization as recognition events to transducing elements in chemical sensors.

Original languageEnglish
Pages (from-to)4254-4263
Number of pages10
JournalSmall (Weinheim an der Bergstrasse, Germany)
Volume12
Issue number31
DOIs
Publication statusPublished - 2016 Aug 1

Fingerprint

Nanowires
DNA
Nanostructures
Self assembly
Silicon
Oligonucleotide Array Sequence Analysis
Static Electricity
Biomolecules
Nucleotides
Coulomb interactions
Polyelectrolytes
Chemical sensors

Keywords

  • conjugated polymers
  • drying-mediated assembly
  • salmon sperm DNA
  • surface patterning

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

Cite this

A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires. / Bae, Dong Geun; Jeong, Ji Eun; Kang, Seok Hee; Byun, Myunghwan; Han, Dong Wook; Lin, Zhiqun; Woo, Han Young; Hong, Suck Won.

In: Small (Weinheim an der Bergstrasse, Germany), Vol. 12, No. 31, 01.08.2016, p. 4254-4263.

Research output: Contribution to journalArticle

Bae, Dong Geun ; Jeong, Ji Eun ; Kang, Seok Hee ; Byun, Myunghwan ; Han, Dong Wook ; Lin, Zhiqun ; Woo, Han Young ; Hong, Suck Won. / A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires. In: Small (Weinheim an der Bergstrasse, Germany). 2016 ; Vol. 12, No. 31. pp. 4254-4263.
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