A novel bioassay platform using ferritin-based nanoprobe hydrogel

Eun Jung Lee, Keum Young Ahn, Jong Hwan Lee, Jin Seung Park, Jong Am Song, Sang Jun Sim, Eun Bong Lee, Young Joo Cha, Jeewon Lee

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Ferritin-based nanoprobe (FBNP) hydrogel provides solutions to some of the traditional problems of bioassays. The schematic shows 3D and highly specific multiplex assays of markers for AIDS and Sjögren's syndrome using quantum-dot based reporters with different fluorescence emissions for the two syndromes. The advantages of using a hydrogel include that the stability of FBNPs is significantly enhanced within the hydrogel, FBNPs are distributed evenly throughout the hydrogel matrix, and the amount of FBNPs within the hydrogel can be well controlled.

Original languageEnglish
Pages (from-to)4739-4744
Number of pages6
JournalAdvanced Materials
Volume24
Issue number35
DOIs
Publication statusPublished - 2012 Sep 11

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Keywords

  • bioassay platforms
  • biomedical applications
  • ferritin
  • hydrogels
  • nanoprobes

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Lee, E. J., Ahn, K. Y., Lee, J. H., Park, J. S., Song, J. A., Sim, S. J., Lee, E. B., Cha, Y. J., & Lee, J. (2012). A novel bioassay platform using ferritin-based nanoprobe hydrogel. Advanced Materials, 24(35), 4739-4744. https://doi.org/10.1002/adma.201200728