A novel synthesis of 5-functionalized oxazolidin-2-ones from enantiomerically pure 2-substituted N-[(R)-(+)-α-methylbenzyl]aziridines

Tae Bo Sim, Se Hun Kang, Kun Su Lee, Won Koo Lee, Hoseop Yun, Yongkwan Dong, Hyun Joon Ha

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

5-Funtionalized enantiomerically pure oxazolidin-2-ones were prepared in one pot from commercially available chiral aziridines bearing an electron-withdrawing group at C-2 with retention of the configuration in high yields by regioselective aziridine ring-opening followed by intramolecular cyclization.

Original languageEnglish
Pages (from-to)104-108
Number of pages5
JournalJournal of Organic Chemistry
Volume68
Issue number1
DOIs
Publication statusPublished - 2003 Jan 10

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'A novel synthesis of 5-functionalized oxazolidin-2-ones from enantiomerically pure 2-substituted N-[(R)-(+)-α-methylbenzyl]aziridines'. Together they form a unique fingerprint.

  • Cite this