Abstract
Deep-brain stimulation (DBS) has been proven as an effective therapy to alleviate Parkinson's disease, tremor, and dystonia. Towards a less invasive head-mounted DBS, we utilize an inductive transcutaneous link to provide sufficient power without size, lifetime, and discomfort of chest-mounted battery-powered traditional DBS. The next step is to adopt aggressive power-management schemes to further improve the DBS efficiency. Current-controlled stimulation (CCS) enables precise charge control and safe operation, but it has low power efficiency due to the dropout voltage across current sources [1,2]. Switched-capacitor stimulation (SCS), proposed in [3], takes advantage of both high efficiency and safety using capacitor banks to transfer charge to the tissue, but it requires an efficient on-chip capacitor charging system, directly from the inductive link. We present an integrated wireless SCS system-on-a-chip with inductive capacitor charging and charge-based stimulation capabilities, which can improve both stimulator (before electrodes) and stimulus (after electrodes) efficiencies in DBS.
| Original language | English |
|---|---|
| Title of host publication | 2014 IEEE International Solid-State Circuits Conference, ISSCC 2014 - Digest of Technical Papers |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | 414-415 |
| Number of pages | 2 |
| ISBN (Print) | 9781479909186 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
| Externally published | Yes |
| Event | 2014 61st IEEE International Solid-State Circuits Conference, ISSCC 2014 - San Francisco, CA, United States Duration: 2014 Feb 9 → 2014 Feb 13 |
Publication series
| Name | Digest of Technical Papers - IEEE International Solid-State Circuits Conference |
|---|---|
| Volume | 57 |
| ISSN (Print) | 0193-6530 |
Other
| Other | 2014 61st IEEE International Solid-State Circuits Conference, ISSCC 2014 |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 14/2/9 → 14/2/13 |
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ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Electrical and Electronic Engineering
Cite this
A power-efficient switched-capacitor stimulating system for electrical/optical deep-brain stimulation. / Lee, Hyung Min; Kwon, Ki Yong; Li, Wen; Ghovanloo, Maysam.
2014 IEEE International Solid-State Circuits Conference, ISSCC 2014 - Digest of Technical Papers. Institute of Electrical and Electronics Engineers Inc., 2014. p. 414-415 6757493 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 57).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - A power-efficient switched-capacitor stimulating system for electrical/optical deep-brain stimulation
AU - Lee, Hyung Min
AU - Kwon, Ki Yong
AU - Li, Wen
AU - Ghovanloo, Maysam
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Deep-brain stimulation (DBS) has been proven as an effective therapy to alleviate Parkinson's disease, tremor, and dystonia. Towards a less invasive head-mounted DBS, we utilize an inductive transcutaneous link to provide sufficient power without size, lifetime, and discomfort of chest-mounted battery-powered traditional DBS. The next step is to adopt aggressive power-management schemes to further improve the DBS efficiency. Current-controlled stimulation (CCS) enables precise charge control and safe operation, but it has low power efficiency due to the dropout voltage across current sources [1,2]. Switched-capacitor stimulation (SCS), proposed in [3], takes advantage of both high efficiency and safety using capacitor banks to transfer charge to the tissue, but it requires an efficient on-chip capacitor charging system, directly from the inductive link. We present an integrated wireless SCS system-on-a-chip with inductive capacitor charging and charge-based stimulation capabilities, which can improve both stimulator (before electrodes) and stimulus (after electrodes) efficiencies in DBS.
AB - Deep-brain stimulation (DBS) has been proven as an effective therapy to alleviate Parkinson's disease, tremor, and dystonia. Towards a less invasive head-mounted DBS, we utilize an inductive transcutaneous link to provide sufficient power without size, lifetime, and discomfort of chest-mounted battery-powered traditional DBS. The next step is to adopt aggressive power-management schemes to further improve the DBS efficiency. Current-controlled stimulation (CCS) enables precise charge control and safe operation, but it has low power efficiency due to the dropout voltage across current sources [1,2]. Switched-capacitor stimulation (SCS), proposed in [3], takes advantage of both high efficiency and safety using capacitor banks to transfer charge to the tissue, but it requires an efficient on-chip capacitor charging system, directly from the inductive link. We present an integrated wireless SCS system-on-a-chip with inductive capacitor charging and charge-based stimulation capabilities, which can improve both stimulator (before electrodes) and stimulus (after electrodes) efficiencies in DBS.
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U2 - 10.1109/ISSCC.2014.6757493
DO - 10.1109/ISSCC.2014.6757493
M3 - Conference contribution
SN - 9781479909186
T3 - Digest of Technical Papers - IEEE International Solid-State Circuits Conference
SP - 414
EP - 415
BT - 2014 IEEE International Solid-State Circuits Conference, ISSCC 2014 - Digest of Technical Papers
PB - Institute of Electrical and Electronics Engineers Inc.
ER -